Detailed information of TA system TA156809

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 1254245..1254406
• Replicon: chromosome
• Accession: NZ_CP053477
• Organism: Staphylococcus warneri strain WB224

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: EYQ96_RS06685
• Protein ID: WP_015364873.1
• Coordinates: 1254245..1254340 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1254372..1254406 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EYQ96_RS06675	1249786..1252719	+	2934	WP_171484933.1	AAA family ATPase	-
EYQ96_RS06680	1252719..1253660	+	942	WP_023373048.1	3'-5' exoribonuclease YhaM	-
EYQ96_RS06685	1254245..1254340	+	96	WP_015364873.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	1254372..1254406	-	35	-	-	Antitoxin
EYQ96_RS06690	1254492..1255484	-	993	WP_002466825.1	peptidylprolyl isomerase	-
EYQ96_RS06695	1255662..1256219	-	558	WP_023373046.1	DUF3267 domain-containing protein	-
EYQ96_RS06700	1256408..1256779	-	372	WP_002452114.1	YtxH domain-containing protein	-
EYQ96_RS06705	1256857..1257282	-	426	WP_023373044.1	HIT family protein	-
EYQ96_RS06710	1257414..1258154	+	741	WP_023373042.1	ABC transporter ATP-binding protein	-
EYQ96_RS06715	1258147..1259370	+	1224	WP_023373041.1	ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3610.26 Da
• Isoelectric Point: 8.0878

>T156809 WP_015364873.1 NZ_CP053477:1254245-1254340 [Staphylococcus warneri]
MTEIFVHIATTVISGCIVTLFAHWLRHRNDK

Nucleotide

• Length: 96 bp

>T156809 NZ_CP069071:2193549-2193926 [Mycobacterium tuberculosis]
GTGCCGCCCCCTGATCCAGCCGCCATGGGTACCTGGAAGTTCTTCCGGGCATCTGTGGATGGCCGGCCGGTATTCAAGAA
GGAGTTCGACAAGCTTCCTGATCAGGCCCGGGCCGCGCTGATCGTGCTAATGCAGCGGTATCTCGTCGGCGACCTCGCCG
CAGGGAGCATCAAACCGATTCGTGGCGACATTCTGGAGTTGCGATGGCATGAGGCGAACAACCACTTCCGGGTACTGTTC
TTCCGCTGGGGCCAGCATCCCGTAGCGCTGACAGCGTTCTACAAGAACCAGCAGAAGACTCCCAAGACGAAGATCGAGAC
GGCCCTGGACCGGCAGAAAATCTGGAAAAGAGCCTTCGGCGACACCCCACCGATCTGA

Antitoxin

Nucleotide

• Length: 35 bp

>AT156809 NZ_CP053477:c1254406-1254372 [Staphylococcus warneri]
ACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin