156805

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 275960..276479 Replicon chromosome
Accession NZ_CP053477
Organism Staphylococcus warneri strain WB224

Toxin (Protein)


Gene name yoeB Uniprot ID A0A2V3ZBG9
Locus tag EYQ96_RS01790 Protein ID WP_023374423.1
Coordinates 276207..276479 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A2V3ZEN9
Locus tag EYQ96_RS01785 Protein ID WP_023374424.1
Coordinates 275960..276214 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EYQ96_RS01770 271481..272803 + 1323 WP_023374427.1 PrsW family intramembrane metalloprotease -
EYQ96_RS01775 272949..273386 + 438 WP_023374426.1 hypothetical protein -
EYQ96_RS01780 273513..275714 - 2202 WP_114599546.1 YSIRK-type signal peptide-containing protein -
EYQ96_RS01785 275960..276214 + 255 WP_023374424.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
EYQ96_RS01790 276207..276479 + 273 WP_023374423.1 Txe/YoeB family addiction module toxin Toxin
EYQ96_RS01795 276721..278091 + 1371 WP_023374422.1 citrate:proton symporter -
EYQ96_RS01800 278184..278822 - 639 WP_023374421.1 NAD(P)H-dependent oxidoreductase -
EYQ96_RS01805 279049..279915 - 867 WP_023374420.1 SDR family NAD(P)-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10878.67 Da        Isoelectric Point: 10.1042

>T156805 WP_023374423.1 NZ_CP053477:276207-276479 [Staphylococcus warneri]
MSRLNILFTPDAFEDYKYWQIHDKKLLKKINHFIKCINRNGPLQGEGKPEALKGNFKGYYSRRINFEHRLVYKVYDSSII
IVSCKYHYFK

Download         Length: 273 bp

>T156805 NZ_CP069071:1767705-1768109 [Mycobacterium tuberculosis]
ATGATCCTCATCGACACATCGGCCTGGGTGGAGTACTTCCGTGCCACCGGATCAATCGCCGCTGTCGAAGTACGCCGGCT
GCTGTCCGAAGAAGCAGCGCGAATCGCTATGTGTGAGCCCATTGCGATGGAAATCTTGAGTGGCGCGCTCGACGACAACA
CCCACACGACGCTAGAGCGGCTCGTGAATGGCTTGCCGTCGTTGAACGTTGATGACGCGATTGACTTTCGTGCTGCCGCG
GGTATCTATCGCGCCGCCCGGCGCGCCGGCGAAACGGTTCGAAGCATCAACGACTGCCTCATAGCGGCGCTCGCGATCCG
CCACGGTGCGCGTATCGTCCACCGTGACGCCGACTTTGATGTGATTGCCCGGATTACCAACCTGCAGGCCGCATCGTTTC
GGTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9371.35 Da        Isoelectric Point: 4.0334

>AT156805 WP_023374424.1 NZ_CP053477:275960-276214 [Staphylococcus warneri]
MAIVSYSIARKNFRSLIDKVNNDSDAVTITTNDSNAVLISESDYNAMMETLYLQQSPANAQHLAKSIEDAERGNTIEVDL
ELYE

Download         Length: 255 bp

>AT156805 NZ_CP069071:1767496-1767699 [Mycobacterium tuberculosis]
ATGTCGCGCACCAACATCGACATCGATGACGAACTTGCCGCCGAGGTCATGCGCAGGTTCGGTCTGACCACCAAGAGGGC
GGCGGTCGACCTTGCCCTACGACGGTTGGTCGGGTCGCCGTTGAGCCGTGAGTTTCTGCTCGGGCTGGAAGGCGTCGGCT
GGGAAGGCGACCTGGATGACTTGCGAAGCGATCGCCCAGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2V3ZBG9

Antitoxin

Source ID Structure
AlphaFold DB A0A2V3ZEN9

References