Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2204010..2204208 Replicon chromosome
Accession NZ_CP053185
Organism Staphylococcus aureus strain Guangzhou-SAU749

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag HLG72_RS10955 Protein ID WP_001802298.1
Coordinates 2204104..2204208 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF
Locus tag -
Coordinates 2204010..2204048 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HLG72_RS10935 2200182..2200847 - 666 WP_001024088.1 SDR family oxidoreductase -
HLG72_RS10940 2200999..2201319 + 321 WP_000139802.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
HLG72_RS10945 2201321..2202298 + 978 WP_000019732.1 CDF family zinc efflux transporter CzrB -
HLG72_RS10950 2202564..2203655 + 1092 WP_170833574.1 transcriptional regulator -
- 2204010..2204048 + 39 - - Antitoxin
HLG72_RS10955 2204104..2204208 - 105 WP_001802298.1 hypothetical protein Toxin
HLG72_RS10960 2204369..2204852 - 484 Protein_2117 recombinase family protein -
HLG72_RS10965 2204895..2206031 - 1137 Protein_2118 SAP domain-containing protein -
HLG72_RS10970 2206320..2206412 + 93 WP_031844941.1 hypothetical protein -
HLG72_RS10975 2207107..2207964 - 858 WP_000370919.1 Cof-type HAD-IIB family hydrolase -
HLG72_RS10980 2208032..2208814 - 783 WP_000908190.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T156216 WP_001802298.1 NZ_CP053185:c2204208-2204104 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T156216 NZ_CP068982:c2263189-2263013 [Bacillus subtilis]
GTGCTTGAGAAAGTGGGTATCATAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGATAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 39 bp

>AT156216 NZ_CP053185:2204010-2204048 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References