Detailed information of TA system TA156179

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2710947..2711239
• Replicon: chromosome
• Accession: NZ_CP053181
• Organism: Enterococcus faecalis strain FMAMOB6

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: HLJ13_RS13175
• Protein ID: WP_021164545.1
• Coordinates: 2710947..2711051 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2710984..2711239 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HLJ13_RS13155	2706187..2706402	-	216	WP_002354768.1	zinc ribbon domain-containing protein	-
HLJ13_RS13160	2706541..2707533	+	993	WP_002398510.1	biotin--[acetyl-CoA-carboxylase] ligase	-
HLJ13_RS13165	2707700..2708338	-	639	WP_002378863.1	lytic polysaccharide monooxygenase	-
HLJ13_RS13170	2709022..2710638	+	1617	WP_002372620.1	phosphatase PAP2/LCP family protein	-
HLJ13_RS13175	2710947..2711051	+	105	WP_021164545.1	putative holin-like toxin	Toxin
-	2710984..2711239	-	256	-	-	Antitoxin
HLJ13_RS13180	2711241..2715020	-	3780	WP_010818049.1	WxL domain-containing protein	-
HLJ13_RS13185	2715615..2715758	+	144	WP_002396786.1	putative holin-like toxin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-34)

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3813.70 Da
• Isoelectric Point: 10.3686

>T156179 WP_021164545.1 NZ_CP053181:2710947-2711051 [Enterococcus faecalis]
MSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 105 bp

>T156179 NZ_CP068830:c671307-670843 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTCTCTTCTTTCGTTACAGCGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACGCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGAGAGACAGAAGAAGCCCATTGA

Antitoxin

Nucleotide

• Length: 256 bp

>AT156179 NZ_CP053181:c2711239-2710984 [Enterococcus faecalis]
ATAAAAATGCCCGAGCCTTGAAATAGGAGGCTCAGGCATTTTTTATTGATGGTCTTTTTAGGGTTGTTGTGCTATAATGA
TAAAGAAAAGAGAGATATGCTTCCAACATATCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCGTGTTAATTATTTAAA
AATAACCGTACTCAGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCAATCAAAGCA
ATGGTAAACATACCAA

Structures

Antitoxin