Detailed information of TA system TA156104

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2223218..2223435
• Replicon: chromosome
• Accession: NZ_CP053101
• Organism: Staphylococcus aureus strain EDCC5398

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: HLB22_RS11020
• Protein ID: WP_075583739.1
• Coordinates: 2223331..2223435 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	2223218..2223273 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HLB22_RS11000	2219340..2220005	-	666	WP_001024097.1	SDR family oxidoreductase	-
HLB22_RS11005	2220157..2220477	+	321	WP_000003755.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
HLB22_RS11010	2220479..2221459	+	981	WP_000019744.1	CDF family zinc efflux transporter CzrB	-
HLB22_RS11015	2221725..2222816	+	1092	WP_000495678.1	hypothetical protein	-
-	2223218..2223273	+	56	-	-	Antitoxin
HLB22_RS11020	2223331..2223435	-	105	WP_075583739.1	hypothetical protein	Toxin
HLB22_RS11025	2223533..2223694	-	162	Protein_2131	helix-turn-helix domain-containing protein	-
HLB22_RS11030	2224112..2224270	+	159	WP_024928151.1	hypothetical protein	-
HLB22_RS11035	2224930..2225787	-	858	WP_000370944.1	Cof-type HAD-IIB family hydrolase	-
HLB22_RS11040	2225855..2226637	-	783	WP_000908181.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3861.73 Da
• Isoelectric Point: 7.0039

>T156104 WP_075583739.1 NZ_CP053101:c2223435-2223331 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISNQGHKK

Nucleotide

• Length: 105 bp

>T156104 NZ_CP068827:c1854355-1853948 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATTCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGCATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGACAGCGGAAAACGGCA
ACATTTATGGCTGGCAGCTGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATATTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin

Nucleotide

• Length: 56 bp

>AT156104 NZ_CP053101:2223218-2223273 [Staphylococcus aureus]
AAAAAGGGCAACACTCAGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin