Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HTH(antitoxin)
Location 98632..99217 Replicon chromosome
Accession NZ_CP053084
Organism Limnobacter sp. SAORIC-580

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag HKT17_RS00440 Protein ID WP_171101316.1
Coordinates 98903..99217 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag HKT17_RS00435 Protein ID WP_171096978.1
Coordinates 98632..98913 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HKT17_RS00400 93945..94589 - 645 WP_171096967.1 MBL fold metallo-hydrolase -
HKT17_RS00405 94691..95020 + 330 WP_171096970.1 DUF2834 domain-containing protein -
HKT17_RS00410 95023..95637 - 615 WP_171096972.1 alternative oxidase -
HKT17_RS00415 95771..96163 + 393 WP_171096974.1 DUF1311 domain-containing protein -
HKT17_RS00420 96300..97211 + 912 WP_171101314.1 NERD domain-containing protein -
HKT17_RS00425 97968..98321 - 354 WP_171096976.1 hypothetical protein -
HKT17_RS00430 98436..98564 + 129 Protein_85 tyrosine-type recombinase/integrase -
HKT17_RS00435 98632..98913 - 282 WP_171096978.1 helix-turn-helix domain-containing protein Antitoxin
HKT17_RS00440 98903..99217 - 315 WP_171101316.1 transcriptional regulator Toxin
HKT17_RS00445 99470..100171 - 702 WP_171096980.1 hypothetical protein -
HKT17_RS00450 100177..100644 - 468 WP_171096982.1 hypothetical protein -
HKT17_RS00455 100645..101520 - 876 WP_171096984.1 ParA family protein -
HKT17_RS00460 101941..103560 - 1620 WP_171096986.1 DUF2326 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(37-81)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11460.08 Da        Isoelectric Point: 8.9373

>T156006 WP_171101316.1 NZ_CP053084:c99217-98903 [Limnobacter sp. SAORIC-580]
VRTVAETPIFQKYASDVWSDAERIEFINWIANNPEAGDVIPGSGGCRKVRWSSAGQGKRGGARVIYFNATEAAIWLLIVY
KKAKFDNLPTAFLAELKKGVEDGL

Download         Length: 315 bp

>T156006 NZ_CP068823:c2192168-2192061 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10191.78 Da        Isoelectric Point: 10.7721

>AT156006 WP_171096978.1 NZ_CP053084:c98913-98632 [Limnobacter sp. SAORIC-580]
MDSEMKKFQDDLLKSVKQMRQGKAARINQVELSPAAEARAKMGLSQQAFASLLGVSVRTLQDWEQGRRSPTGAAKTLLKV
AVSHPEVLREIGA

Download         Length: 282 bp

>AT156006 NZ_CP068823:2192218-2192281 [Escherichia coli]
TCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTAAACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References