Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HTH(antitoxin)
Location 98632..99217 Replicon chromosome
Accession NZ_CP053084
Organism Limnobacter sp. SAORIC-580

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag HKT17_RS00440 Protein ID WP_171101316.1
Coordinates 98903..99217 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag HKT17_RS00435 Protein ID WP_171096978.1
Coordinates 98632..98913 (-) Length 94 a.a.

Genomic Context

HKT17_RS00405HKT17_RS00415HKT17_RS00420HKT17_RS00430HKT17_RS00400HKT17_RS00410HKT17_RS00425HKT17_RS00435HKT17_RS00440HKT17_RS00445HKT17_RS00450HKT17_RS00455HKT17_RS00460
Location: 94691..95020 (330 bp)
Type: Others
Protein ID: WP_171096970.1
Location: 95771..96163 (393 bp)
Type: Others
Protein ID: WP_171096974.1
Location: 96300..97211 (912 bp)
Type: Others
Protein ID: WP_171101314.1
Location: 98436..98564 (129 bp)
Type: Others
Protein ID: Protein_85
Location: 93945..94589 (645 bp)
Type: Others
Protein ID: WP_171096967.1
Location: 95023..95637 (615 bp)
Type: Others
Protein ID: WP_171096972.1
Location: 97968..98321 (354 bp)
Type: Others
Protein ID: WP_171096976.1
Location: 98632..98913 (282 bp)
Type: Antitoxin
Protein ID: WP_171096978.1
Location: 98903..99217 (315 bp)
Type: Toxin
Protein ID: WP_171101316.1
Location: 99470..100171 (702 bp)
Type: Others
Protein ID: WP_171096980.1
Location: 100177..100644 (468 bp)
Type: Others
Protein ID: WP_171096982.1
Location: 100645..101520 (876 bp)
Type: Others
Protein ID: WP_171096984.1
Location: 101941..103560 (1620 bp)
Type: Others
Protein ID: WP_171096986.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HKT17_RS0040093945..94589-645WP_171096967.1MBL fold metallo-hydrolase-
HKT17_RS0040594691..95020+330WP_171096970.1DUF2834 domain-containing protein-
HKT17_RS0041095023..95637-615WP_171096972.1alternative oxidase-
HKT17_RS0041595771..96163+393WP_171096974.1DUF1311 domain-containing protein-
HKT17_RS0042096300..97211+912WP_171101314.1NERD domain-containing protein-
HKT17_RS0042597968..98321-354WP_171096976.1hypothetical protein-
HKT17_RS0043098436..98564+129Protein_85tyrosine-type recombinase/integrase-
HKT17_RS0043598632..98913-282WP_171096978.1helix-turn-helix domain-containing proteinAntitoxin
HKT17_RS0044098903..99217-315WP_171101316.1transcriptional regulatorToxin
HKT17_RS0044599470..100171-702WP_171096980.1hypothetical protein-
HKT17_RS00450100177..100644-468WP_171096982.1hypothetical protein-
HKT17_RS00455100645..101520-876WP_171096984.1ParA family protein-
HKT17_RS00460101941..103560-1620WP_171096986.1DUF2326 domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(37-81)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11460.08 Da        Isoelectric Point: 8.9373

>T156006 WP_171101316.1 NZ_CP053084:c99217-98903 [Limnobacter sp. SAORIC-580]
VRTVAETPIFQKYASDVWSDAERIEFINWIANNPEAGDVIPGSGGCRKVRWSSAGQGKRGGARVIYFNATEAAIWLLIVY
KKAKFDNLPTAFLAELKKGVEDGL

Download         Length: 315 bp

>T156006 NZ_CP068823:c2192168-2192061 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10191.78 Da        Isoelectric Point: 10.7721

>AT156006 WP_171096978.1 NZ_CP053084:c98913-98632 [Limnobacter sp. SAORIC-580]
MDSEMKKFQDDLLKSVKQMRQGKAARINQVELSPAAEARAKMGLSQQAFASLLGVSVRTLQDWEQGRRSPTGAAKTLLKV
AVSHPEVLREIGA

Download         Length: 282 bp

>AT156006 NZ_CP068823:2192218-2192281 [Escherichia coli]
TCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTAAACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References