Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 329635..329857 Replicon chromosome
Accession NZ_CP053080
Organism Escherichia coli strain HB37

Toxin (Protein)


Gene name ldrD Uniprot ID S1NWX0
Locus tag HKW69_RS01660 Protein ID WP_001295224.1
Coordinates 329750..329857 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 329635..329701 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HKW69_RS01640 325076..325978 + 903 WP_000084677.1 dipeptide ABC transporter permease DppC -
HKW69_RS01645 325989..326972 + 984 WP_001196477.1 dipeptide ABC transporter ATP-binding protein -
HKW69_RS01650 326969..327973 + 1005 WP_000103577.1 dipeptide ABC transporter ATP-binding subunit DppF -
HKW69_RS01655 328003..329274 - 1272 WP_001298005.1 amino acid permease -
- 329635..329701 - 67 - - Antitoxin
HKW69_RS01660 329750..329857 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
HKW69_RS01665 329944..331623 - 1680 Protein_328 cellulose biosynthesis protein BcsG -
HKW69_RS01670 331620..331811 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
HKW69_RS01675 331808..333379 - 1572 WP_001204945.1 cellulose biosynthesis protein BcsE -
HKW69_RS01680 333652..333840 + 189 WP_001063314.1 YhjR family protein -
HKW69_RS01685 333852..334604 + 753 WP_000279536.1 cellulose biosynthesis protein BcsQ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3882.70 Da        Isoelectric Point: 9.0157

>T155962 WP_001295224.1 NZ_CP053080:329750-329857 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T155962 NZ_CP068821:3832694-3832912 [Escherichia coli]
ATGTCCGAAAAACCTTTAACAAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 67 bp

>AT155962 NZ_CP053080:c329701-329635 [Escherichia coli]
GTCTAGGTTCAAGATTAGCCCCCGTGATATTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TSJ7

Antitoxin

Download structure file

References