Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2281289..2281505 Replicon chromosome
Accession NZ_CP053075
Organism Staphylococcus aureus strain SA01

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag HK402_RS11520 Protein ID WP_001802298.1
Coordinates 2281401..2281505 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2281289..2281344 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HK402_RS11500 2277494..2278159 - 666 WP_001024092.1 SDR family oxidoreductase -
HK402_RS11505 2278311..2278631 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
HK402_RS11510 2278633..2279610 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
HK402_RS11515 2279876..2280967 + 1092 WP_000495669.1 hypothetical protein -
- 2281289..2281344 + 56 - - Antitoxin
HK402_RS11520 2281401..2281505 - 105 WP_001802298.1 hypothetical protein Toxin
HK402_RS11525 2282185..2282343 + 159 WP_001792784.1 hypothetical protein -
HK402_RS11530 2283001..2283858 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
HK402_RS11535 2283926..2284708 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T155929 WP_001802298.1 NZ_CP053075:c2281505-2281401 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T155929 NZ_CP068820:c2786020-2785847 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 56 bp

>AT155929 NZ_CP053075:2281289-2281344 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References