Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 118530..119218 Replicon chromosome
Accession NZ_CP053073
Organism Usitatibacter palustris strain Swamp67

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag DSM104440_RS00565 Protein ID WP_171159771.1
Coordinates 118530..118874 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag DSM104440_RS00570 Protein ID WP_171159773.1
Coordinates 118871..119218 (+) Length 116 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DSM104440_RS00535 113926..114822 + 897 WP_171159759.1 EAL domain-containing protein -
DSM104440_RS00540 114949..116043 + 1095 WP_171159761.1 hypothetical protein -
DSM104440_RS00545 116173..116475 + 303 WP_171159763.1 hypothetical protein -
DSM104440_RS00550 116666..117289 + 624 WP_171159765.1 N-methyl-D-aspartate receptor NMDAR2C subunit -
DSM104440_RS00555 117380..117868 + 489 WP_171159767.1 hypothetical protein -
DSM104440_RS00560 117868..118455 + 588 WP_171159769.1 GNAT family N-acetyltransferase -
DSM104440_RS00565 118530..118874 + 345 WP_171159771.1 toxin Toxin
DSM104440_RS00570 118871..119218 + 348 WP_171159773.1 transcriptional regulator Antitoxin
DSM104440_RS00575 119373..119933 - 561 WP_171159775.1 hypothetical protein -
DSM104440_RS19200 119921..120427 - 507 WP_212758153.1 DUF2778 domain-containing protein -
DSM104440_RS00585 120480..121382 - 903 WP_212758154.1 hypothetical protein -
DSM104440_RS00590 121370..121888 - 519 WP_171159779.1 RHS repeat-associated core domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 99282..138704 39422


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13402.25 Da        Isoelectric Point: 10.2169

>T155913 WP_171159771.1 NZ_CP053073:118530-118874 [Usitatibacter palustris]
MKAVFVELPAFARHRADYFDDSAFTRLQVELMKNPEGGDLIRDSGGLRKLRFPDARRGKGKRGGLRVIYYWWDSESQFWL
FTVYDKDQADDLSPEQRRTLKGLMKAELEARSRR

Download         Length: 345 bp

>T155913 NZ_CP068820:103892-104143 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TGCTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Antitoxin


Download         Length: 116 a.a.        Molecular weight: 12658.85 Da        Isoelectric Point: 11.6549

>AT155913 WP_171159773.1 NZ_CP053073:118871-119218 [Usitatibacter palustris]
MNTKAKSVGKLGRKRDVFAELKEGMDALSAARAGKVTLRTHSVKVKPAPTLSPKELVRVREGLHISRAVFAAYLRTNVRT
LENWEQGRAKPNAQAALLISLVKQFPDTVQRLAAI

Download         Length: 348 bp

>AT155913 NZ_CP068820:104140-104394 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAATGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References