Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 150257..150759 Replicon chromosome
Accession NZ_CP053044
Organism Proteus terrae subsp. cibarius strain HNCF43W

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag HG541_RS00660 Protein ID WP_075671248.1
Coordinates 150257..150511 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag HG541_RS00665 Protein ID WP_072068851.1
Coordinates 150508..150759 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HG541_RS00635 145591..146088 - 498 WP_075671238.1 Der GTPase-activating protein YihI -
HG541_RS00640 146277..147749 + 1473 WP_075671240.1 glycosyltransferase family 39 protein -
HG541_RS00645 147752..148300 + 549 WP_075671242.1 GNAT family N-acetyltransferase -
HG541_RS00650 148350..148661 - 312 WP_075671244.1 monooxygenase -
HG541_RS00655 148742..150100 - 1359 WP_075671246.1 NCS2 family permease -
HG541_RS00660 150257..150511 - 255 WP_075671248.1 Txe/YoeB family addiction module toxin Toxin
HG541_RS00665 150508..150759 - 252 WP_072068851.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
HG541_RS00670 150990..151742 - 753 WP_159242128.1 amino acid ABC transporter permease -
HG541_RS00675 151744..152481 - 738 WP_075671252.1 amino acid ABC transporter permease -
HG541_RS00680 152588..153427 - 840 WP_036933789.1 ABC transporter substrate-binding protein -
HG541_RS00685 153643..154377 - 735 WP_075671254.1 phosphate signaling complex protein PhoU -
HG541_RS00690 154392..155168 - 777 WP_006534565.1 phosphate ABC transporter ATP-binding protein PstB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10170.78 Da        Isoelectric Point: 9.9411

>T155857 WP_075671248.1 NZ_CP053044:c150511-150257 [Proteus terrae subsp. cibarius]
MKLIFSEQSWSDYLYWQQIDKKIIKRINELIKDIKRTPFSGIGKPEPLKHNLAGFWSRRITDEHRLIYRITDSAIEIASC
RYHY

Download         Length: 255 bp

>T155857 NZ_CP068818:205306-205491 [Escherichia coli]
GTGAAAAGTGCAGACGTGATCGCCATCCTGAAGCAGCATGGCTGGGAACATATTCGAACCCGTGGCAGTCATCATCAGTT
CCGCCACCCTGTTCATCCGGGTCTGGTGACGGTTCCGCACCCTAAAAAAGATATTAAGCCCGGTACGCTGGCGCAAATTG
GGCGTCAGGCTGGTTTAACATTTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9463.77 Da        Isoelectric Point: 4.4354

>AT155857 WP_072068851.1 NZ_CP053044:c150759-150508 [Proteus terrae subsp. cibarius]
MKTINYTEARQNLTSIMNETIDDRVPIMITRQKGIPCVLLSLDEYQALEETAYLLRSPANARHLLDSIDELNQGKGIEKD
ITE

Download         Length: 252 bp

>AT155857 NZ_CP068818:205508-205918 [Escherichia coli]
ATGTTTTATCCCGCCTATATCCACAGTGATCCTGACGGCAGCGCCAGCGGTTTTTTCCCTGATGTTCCAGGCTGTTATTT
TGCTGGTGATACGCTGGACAACGCTTTCCAGGATGCGCGAAGTGCACTGGTCGCGCACTTCGAAACCTTATGCGAGATGA
ATGAAGAGTTGCCGCTTCCAGGCTCTGTGGAAACACATCTGGTCCAGCGTGCGCAGGACTTTATTGGTGGGCAATGGTTG
CTGGTGGATATCAATATGAATCAGTTCGAAGGTCGGGCTGAACGTATCAATATTACGATGCCGAAAAGGTTACTGAACAA
GATTGATACCTACGTGCGCAATAACCCAGACTACGCCAACAGAAGTGCGTTTCTGGCAGAAGCTGCCCGGCGTGTATTGC
CGGGCGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References