Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 2466025..2466840 Replicon chromosome
Accession NZ_CP053042
Organism Proteus terrae subsp. cibarius strain HNCF44W

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag HG539_RS11335 Protein ID WP_075673429.1
Coordinates 2466025..2466498 (-) Length 158 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag HG539_RS11340 Protein ID WP_075673430.1
Coordinates 2466505..2466840 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HG539_RS11320 2461847..2464042 - 2196 WP_099659727.1 flotillin family protein -
HG539_RS11325 2464129..2464764 - 636 WP_156734149.1 DUF1449 family protein -
HG539_RS11330 2465067..2465714 - 648 WP_075673428.1 CPBP family intramembrane metalloprotease -
HG539_RS11335 2466025..2466498 - 474 WP_075673429.1 type II toxin-antitoxin system YhaV family toxin Toxin
HG539_RS11340 2466505..2466840 - 336 WP_075673430.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
HG539_RS11350 2467487..2468059 - 573 WP_075673431.1 transcriptional regulator -
HG539_RS11355 2468243..2469568 - 1326 WP_036934359.1 anaerobic C4-dicarboxylate transporter -
HG539_RS11360 2469727..2471151 - 1425 WP_072069056.1 aspartate ammonia-lyase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-147)

Antitoxin

PrlF antitoxin

(15-109)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 18639.26 Da        Isoelectric Point: 9.2715

>T155853 WP_075673429.1 NZ_CP053042:c2466498-2466025 [Proteus terrae subsp. cibarius]
MDFPTDLNGWTIYAHPCFKQQYDELLQKVEALKKKYPEDYQKKADTKIFAHVLKSIVNITNDPRAPEFRLGNTLGEENKN
WSRIKLVNGRYRLFFRFSFKEKIIILAWINDNDTLRTYGNKTDAYRVFEKKLKKGHPPKNWNDLFSDCINEADCQDP

Download         Length: 474 bp

>T155853 NZ_CP068817:c4435778-4435401 [Escherichia coli]
ATGAACACATTACCCGATACACACATACGGGAGGCATCGCATTGCCAGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCATTACGGCCTCACACTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTTGAAAAATACGCACTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACTCGTTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCCCGCCGGGCAACCGGCCTGATGGCCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAACATCCGGGGGCGAAACAATGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12312.67 Da        Isoelectric Point: 4.2560

>AT155853 WP_075673430.1 NZ_CP053042:c2466840-2466505 [Proteus terrae subsp. cibarius]
MLTHVCTDNIALEADSKITERHQTTIPASIREALHLSGGDRIHYKLLSTGDVLISRHSDGSEDPVMASFLNFLAQDITNH
PQTIQPLDISRGFELVEGMDINLDDDITDNE

Download         Length: 336 bp

>AT155853 NZ_CP068817:c4436236-4435868 [Escherichia coli]
GTGTCAGACACTCTCCCCGGGACAACGCATCCCGACGATAACAACGACCGCCCCTGGTGGGGGCTACCCTGCACCGTGAC
GCCCTGTTTTGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCAGACCGCGCCGGTATCAGAGGCCGGT
TCAGCGACGCGGATGCGTACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAAGGCTGACCTGCGAAGCCGACACCCTCGGCAGTTG
TGGCTACGTTTATATGGCTGTTTATCCGACGCCCGAAACGAAAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References