Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 140836..141530 Replicon chromosome
Accession NZ_CP053014
Organism Dickeya zeae strain MS_2018

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag HJ586_RS00620 Protein ID WP_236306793.1
Coordinates 141132..141530 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID -
Locus tag HJ586_RS00615 Protein ID WP_236305927.1
Coordinates 140836..141129 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HJ586_RS00590 (HJ586_00590) 135900..137150 + 1251 WP_236305925.1 esterase FrsA -
HJ586_RS00595 (HJ586_00595) 137401..137760 + 360 WP_102802226.1 sigma factor-binding protein Crl -
HJ586_RS00600 (HJ586_00600) 137888..138991 + 1104 WP_012885880.1 glutamate 5-kinase -
HJ586_RS00605 (HJ586_00605) 139002..140255 + 1254 WP_236305926.1 glutamate-5-semialdehyde dehydrogenase -
HJ586_RS00615 (HJ586_00615) 140836..141129 + 294 WP_236305927.1 type I toxin-antitoxin system antitoxin YafN Antitoxin
HJ586_RS00620 (HJ586_00620) 141132..141530 + 399 WP_236306793.1 type II toxin-antitoxin system YafO family toxin Toxin
HJ586_RS00625 (HJ586_00625) 141871..142068 + 198 WP_236305928.1 hypothetical protein -
HJ586_RS00630 (HJ586_00630) 142468..142647 - 180 WP_236305929.1 CRISPR-associated endonuclease Cas2 -
HJ586_RS00635 (HJ586_00635) 142640..143521 - 882 WP_236305930.1 CRISPR-associated endonuclease Cas1 -
HJ586_RS00640 (HJ586_00640) 144376..145299 + 924 WP_236305931.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(27-130)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15343.66 Da        Isoelectric Point: 8.8093

>T155763 WP_236306793.1 NZ_CP053014:141132-141530 [Dickeya zeae]
IRIFKSTLIRQQLSPQELDDLVADFLSYKKEGVLPDTFGRDAPYDDDRTYPLVKKEQVSHIHLADADAPFPKFLRQFKRT
RDQAHLVYCQGASDPDAYLLIIILKPEAHKMARNNNHMHKIGVMAEAFRMKY

Download         Length: 399 bp

>T155763 NZ_CP068814:2020288-2020539 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATCATTGAGTGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11032.50 Da        Isoelectric Point: 4.7049

>AT155763 WP_236305927.1 NZ_CP053014:140836-141129 [Dickeya zeae]
MERILAEKSINITELRKNPAKYFIDEPVAVLSNNRPAGYMVSAKVFEELIDLLEEKQGRVYTAARFRPTAERLSEIAQNG
QTLLQNASDKDLTEFSE

Download         Length: 294 bp

>AT155763 NZ_CP068814:2020536-2020790 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGACGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References