Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 3566667..3567361 Replicon chromosome
Accession NZ_CP053013
Organism Dickeya zeae strain MS_2014

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag HJ580_RS15965 Protein ID WP_102802202.1
Coordinates 3566667..3567071 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID -
Locus tag HJ580_RS15970 Protein ID WP_102802203.1
Coordinates 3567068..3567361 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HJ580_RS15950 (HJ580_15965) 3563416..3564180 + 765 WP_012885864.1 SDR family oxidoreductase -
HJ580_RS15955 (HJ580_15970) 3564213..3565094 + 882 WP_102802200.1 methylated-DNA--[protein]-cysteine S-methyltransferase -
HJ580_RS15960 (HJ580_15975) 3565109..3566317 - 1209 WP_199770299.1 MFS transporter -
HJ580_RS15965 (HJ580_15980) 3566667..3567071 - 405 WP_102802202.1 type II toxin-antitoxin system YafO family toxin Toxin
HJ580_RS15970 (HJ580_15985) 3567068..3567361 - 294 WP_102802203.1 type I toxin-antitoxin system antitoxin YafN Antitoxin
HJ580_RS15975 (HJ580_15990) 3567923..3569242 + 1320 WP_102802204.1 site-specific integrase -
HJ580_RS15980 (HJ580_15995) 3569317..3570366 - 1050 WP_102802205.1 macro domain-containing protein -
HJ580_RS15985 (HJ580_16000) 3570380..3571027 - 648 WP_102802206.1 DUF4433 domain-containing protein -
HJ580_RS15990 (HJ580_16005) 3571132..3571965 - 834 WP_102802207.1 DUF4942 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(29-132)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15494.82 Da        Isoelectric Point: 8.0873

>T155761 WP_102802202.1 NZ_CP053013:c3567071-3566667 [Dickeya zeae]
MSFRIFKSTLIRQQLSQKELDDLVVDFLSYKKEGVLPDTFGRDAPYDDDRTYPLVKEEQVAHIHLADAGAPFPKFLRQFK
RTSDQAHLVYCQGASDPDAYLLIIILKPEAHKMARNNNHMHKIGVIAEAFRMKY

Download         Length: 405 bp

>T155761 NZ_CP068814:1224479-1224814 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCCGG
ACATCGTCCGGCTGTTGTCCTGAGTCCGTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACGGTTGCCCCAGAGGAATTACAGCTCATTAAAGCCAAAATTAA
CGTGCTGATTGGGTAG

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11006.46 Da        Isoelectric Point: 4.9062

>AT155761 WP_102802203.1 NZ_CP053013:c3567361-3567068 [Dickeya zeae]
MERILAEKSINITELRKNPAKYFIDEPVAVLSNNRPAGYMVSAKVFEELIDLLEEKQGRLHTAARFRPSAERLSEIAQNG
QTLLQNASDKDLTEFSE

Download         Length: 294 bp

>AT155761 NZ_CP068814:1224231-1224479 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References