155746

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 3716697..3717391 Replicon chromosome
Accession NZ_CP053012
Organism Dickeya zeae MS1

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag J417_RS16725 Protein ID WP_026357962.1
Coordinates 3716697..3717095 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID -
Locus tag J417_RS16730 Protein ID WP_019845255.1
Coordinates 3717098..3717391 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J417_RS16700 (J417_16720) 3712455..3713663 - 1209 WP_033581679.1 MFS transporter -
J417_RS16705 (J417_16725) 3714109..3714576 + 468 WP_019845258.1 hypothetical protein -
J417_RS16710 (J417_16730) 3714714..3714938 - 225 Protein_3267 transposase -
J417_RS16715 (J417_16735) 3715392..3716159 - 768 WP_236377647.1 hypothetical protein -
J417_RS16720 (J417_16740) 3716384..3716491 - 108 Protein_3269 TA system toxin CbtA family protein -
J417_RS16725 (J417_16745) 3716697..3717095 - 399 WP_026357962.1 type II toxin-antitoxin system YafO family toxin Toxin
J417_RS16730 (J417_16750) 3717098..3717391 - 294 WP_019845255.1 type I toxin-antitoxin system antitoxin YafN Antitoxin
J417_RS16740 (J417_16760) 3717976..3719229 - 1254 WP_019845254.1 glutamate-5-semialdehyde dehydrogenase -
J417_RS16745 (J417_16765) 3719240..3720343 - 1104 WP_012885880.1 glutamate 5-kinase -
J417_RS16750 (J417_16770) 3720471..3720830 - 360 WP_026357961.1 sigma factor-binding protein Crl -
J417_RS16755 (J417_16775) 3721095..3722345 - 1251 WP_019845251.1 esterase FrsA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(27-130)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15296.54 Da        Isoelectric Point: 7.4698

>T155746 WP_026357962.1 NZ_CP053012:c3717095-3716697 [Dickeya zeae MS1]
IRIFKSTLIRQQLSPQELDDLVADFLSYKKDGVLPDTFGRDAPYDDDRTYPLVKEEQVAHIHLADADAPFPKFLRQFKRT
RDQAHLVYCQGASDPDAYLLIIILKPEAHKMARNNNHMHKIGVIAEAFRMKY

Download         Length: 399 bp

>T155746 NZ_CP068813:c4128289-4127369 [Escherichia coli]
ATGGATCTGCGTGATAGCTATGCCCGGCAGGTCAAACTGTTGATGGCCGCTCTGCCGTATGTGGCGAAGGAGTCCTGTTT
CGCGTTGAAAGGCGGCACCGCAATCAATTTGTTTGTGCAGGATTTTCCCCGTCTGTCGGTGGATATTGATCTGGCGTACA
AGAGCTTTGCGGATCGCGATACTGATTTGGCGGCTATCAACGACGCTTTGAAGAGGATTACTGCATCGCTGAACGGCAGA
CCGGGGATCACCGCGATTCGGCAGGAAAATAAAGCGGATGAAAAGCGCATCATTGTGAATACCGCTGATGCAAAGATTAA
GATCGAGGTTAGCCCGGTCTGGCGCGGGCTGTTGTTGCCTCCGGCAGAAATGCCTGTGTGCGAACGTGTGGAAATGGAGT
ATGGCTTCACCACCATGAGTGTCGTCTCGCTGGCGGATCTTTATGGCGGTAAAATCTGCGCTGCGCTTGATCGTCAGCAC
CCGCGCGATCTGTTTGATGTGCTGAATATGCTGGAGAAACCGGGACTGATGCGGGAGATCTTTGACGGTTTTCTTTGTTA
TCTGGCAGGCCATCCCCGCCCCATCGCCGAGTTGCTGGCTCCAAACTGGGATACAGAGCGGATCGCCACGTTGTACGCGC
AGGAATTTTCAGGGATGACGCAACAGGAAACGTCGCTGGAATCGCTTCTGTCAGTAACGACTTTGCTGCCGCAGGCGTTG
AAGTCACATCTTACGGATCTGGATCGCGAGTTCTTGCTCAGTTTTAAGCAAAACAGCCCTGACTGGTCGCGGTATCGCTA
TCCTGAAATTCAGCATCTTCCGGCTATTCGCTGGAAGCAACGCAATCTGGCGGTGCTTAAAGATAAAAATCCGGCGAAGT
ATGTGGCGGCGGTGAATAAGCTAGAGAGGGTTCTGGCGTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11061.54 Da        Isoelectric Point: 5.2187

>AT155746 WP_019845255.1 NZ_CP053012:c3717391-3717098 [Dickeya zeae MS1]
MERILAEKSINITELRKNPAKYFIDEPVAVLSNNRPAGYMVSAKVFEELIDLLEEKQGRVHTAARFRPSAERLREVAQNG
QTLLQNASDKDLTEFTE

Download         Length: 294 bp

>AT155746 NZ_CP068813:c4129058-4128276 [Escherichia coli]
TTGCCAAACTATCTAAACTGGCTGATGCAGCACACGCTACCCGGCCAGGTGCTGCTCCAGTCATGGCTTACCCGCAACGG
CATAGATCGTAAGCTCTCTTATCTCTATGTGAAGAATGGCTGGCTCAGGCGGATCGCTCACGGCGTATACTGCCGGACGG
GTCGTGAACCGGATTGGGTGGATGCGGTTTACTGCCTGCAATCGCAGTGGGAAAAGCCTGTTCGGGTGGCGGGGCTAACC
AGCCTTGCGCTTCAGGGTCATGCGCACTATACCGAACAGGGTAAGCCGCAGGTCTGGCTCGCGCTTCCGGCTTACGTCAA
ACTGCCGGGATGGTTTTCTGCCTTTGAACAATCCGCAACGTTTGTCACGCTGTATACGTCAGGCCTTACCGCTGATGTAA
CGCCATTTACTACGGAACTGAAAATTGGCGACCGCCAGTTAGCAGGCAGTGTTCCGGAACTGGCCGCGTATGAGATCGCC
TGCGGCGTTCCTTCGTTAATCTCGTTCGAACATGCCGATGCTCTGTTTCAGGGGTTGAATCTTCTCAGCCCACGCAAATT
GCAGGCACTGCTTCGCGCCAGCCATTCGGTTAAAACCAACCGGGTGATGCTTTACCTTGCCCGGCGTAATGGACACCCTT
ATTTTCAGTATATTGATCAAAGCGGTATAGAAACAGGTACGGGAAAGCGGCAAATCATACCCGGCGGCTGGCTGGAGCCG
GATTATCAAATTACTGTTCCACGCGCATTTAAACCGGAAGGAGTCGAAGATGGATCTGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References