Detailed information of TA system TA155658

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/-
• Location: 6863767..6864421
• Replicon: chromosome
• Accession: NZ_CP052860
• Organism: Pseudomonas sp. ADAK13

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: HKK54_RS31775
• Protein ID: WP_169389034.1
• Coordinates: 6863767..6864117 (+)
• Length: 117 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: A0A7Z3ATS4
• Locus tag: HKK54_RS31780
• Protein ID: WP_010172763.1
• Coordinates: 6864107..6864421 (+)
• Length: 105 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HKK54_RS31765	6860525..6862057	+	1533	WP_010172759.1	NADH-quinone oxidoreductase subunit M	-
HKK54_RS31770	6862065..6863528	+	1464	WP_010172761.1	NADH-quinone oxidoreductase subunit NuoN	-
HKK54_RS31775	6863767..6864117	+	351	WP_169389034.1	toxin	Toxin
HKK54_RS31780	6864107..6864421	+	315	WP_010172763.1	XRE family transcriptional regulator	Antitoxin
HKK54_RS31785	6864481..6866160	-	1680	WP_169389035.1	methyl-accepting chemotaxis protein	-
HKK54_RS31790	6866230..6867549	-	1320	WP_169389406.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 117 a.a.
• Molecular weight: 13771.62 Da
• Isoelectric Point: 9.9312

>T155658 WP_169389034.1 NZ_CP052860:6863767-6864117 [Pseudomonas sp. ADAK13]
MDALFIELPAFERHRRDYLNDELFHGFQQALMRNPQAGDVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHEQDDLSTQHKTALKHLLDREIKARKSYET

Nucleotide

• Length: 351 bp

>T155658 NZ_CP068810:c4102353-4101955 [Escherichia coli]
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAACTTGATGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGCGATGCACTCTACGACGACTCGTTTACCTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGTGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGAAGCGCATTTGGTATATTGTCAGGGTGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAGCCTGA
ACCTCATAAACTGGCTCGAGATAACAACCAAATGCATAAAATTGGAAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA

Antitoxin

Protein

• Length: 105 a.a.
• Molecular weight: 11753.51 Da
• Isoelectric Point: 9.9896

>AT155658 WP_010172763.1 NZ_CP052860:6864107-6864421 [Pseudomonas sp. ADAK13]
MKRDIFSELVEGFDALADERQGKVTLRSHKVQLSKLAPLTADEVVAVRQQLNLSRSVFAMYLRTNTRTLENWEQGRATPN
AQAATLIRLVAQFPETVERLALLT

Nucleotide

• Length: 315 bp

>AT155658 NZ_CP068810:c4102649-4102356 [Escherichia coli]
ATGCATCGAATTCTCGCTGAAAAATCGGTCAATATCACTGAGTTACGTAAAAATCCAGCAAAATACTTTATTGATCAACC
GGTTGCGGTTCTTTCTAATAATCGCCCCGCAGGATATCTCTTAAGTGCCAGCGCATTCGAAGCGTTAATGGACATGCTTG
CAGAACAAGAGGAGAAAAAACTGGTGAAGGCGCGCTTCCGTCCGAGTGCCGCAAGATTAGAGGAAATTACACGCCGCGCT
GAACAATATCTTAATGATATGACGGATGATGATTTCAATGACTTTAAGGAATAA

Structures

Antitoxin

• AlphaFold DB: A0A7Z3ATS4