Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
Location | 234401..234968 | Replicon | chromosome |
Accession | NZ_CP052854 | ||
Organism | Xylella fastidiosa subsp. multiplex strain LM10 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | HKJ32_RS00975 | Protein ID | WP_004085174.1 |
Coordinates | 234687..234968 (-) | Length | 94 a.a. |
Antitoxin (Protein)
Gene name | graA | Uniprot ID | - |
Locus tag | HKJ32_RS00970 | Protein ID | WP_004085172.1 |
Coordinates | 234401..234676 (-) | Length | 92 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HKJ32_RS00940 | 230295..232169 | + | 1875 | WP_169709907.1 | phage major capsid protein | - |
HKJ32_RS00945 | 232187..232447 | + | 261 | WP_012337650.1 | hypothetical protein | - |
HKJ32_RS00950 | 232447..232770 | + | 324 | WP_169709908.1 | hypothetical protein | - |
HKJ32_RS00955 | 232767..233294 | + | 528 | WP_169709909.1 | hypothetical protein | - |
HKJ32_RS00960 | 233270..233812 | + | 543 | WP_154436958.1 | hypothetical protein | - |
HKJ32_RS00965 | 233809..234396 | + | 588 | WP_042836490.1 | phage baseplate assembly protein V | - |
HKJ32_RS00970 | 234401..234676 | - | 276 | WP_004085172.1 | HigA family addiction module antidote protein | Antitoxin |
HKJ32_RS00975 | 234687..234968 | - | 282 | WP_004085174.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
HKJ32_RS00980 | 235166..235504 | + | 339 | WP_004088650.1 | GPW/gp25 family protein | - |
HKJ32_RS00985 | 235504..236397 | + | 894 | WP_038284057.1 | baseplate J/gp47 family protein | - |
HKJ32_RS00990 | 236390..236947 | + | 558 | WP_169709910.1 | phage tail protein I | - |
HKJ32_RS00995 | 236955..238547 | + | 1593 | WP_169709911.1 | tail fiber domain-containing protein | - |
HKJ32_RS01000 | 238612..239790 | + | 1179 | WP_038230457.1 | phage tail sheath family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 201218..247924 | 46706 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 10610.17 Da Isoelectric Point: 9.8829
>T155619 WP_004085174.1 NZ_CP052854:c234968-234687 [Xylella fastidiosa subsp. multiplex]
MIKSFRHKGIQQFFLVGSTAGIQTKHAAKLRIQLTALESAKRPEDMNAPGWKLHPLKGADLKGHWSIWVNGNYRLTFAFE
GEDAILVDYQDYH
MIKSFRHKGIQQFFLVGSTAGIQTKHAAKLRIQLTALESAKRPEDMNAPGWKLHPLKGADLKGHWSIWVNGNYRLTFAFE
GEDAILVDYQDYH
Download Length: 282 bp
>T155619 NZ_CP068809:1929689-1929940 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA
Antitoxin
Download Length: 92 a.a. Molecular weight: 10072.68 Da Isoelectric Point: 10.2184
>AT155619 WP_004085172.1 NZ_CP052854:c234676-234401 [Xylella fastidiosa subsp. multiplex]
MKRMHNPAHPGEVLREYLGELTVTNAAAKLGVSRVALSRILNGTNGISADMALRLEDALGTSAEMWAAMQFKYDLWVASQ
QPRPKITRLHV
MKRMHNPAHPGEVLREYLGELTVTNAAAKLGVSRVALSRILNGTNGISADMALRLEDALGTSAEMWAAMQFKYDLWVASQ
QPRPKITRLHV
Download Length: 276 bp
>AT155619 NZ_CP068809:1929937-1930191 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAAATTATCAAAGATACACGCAGAACACCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GCTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAAATTATCAAAGATACACGCAGAACACCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GCTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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