Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 101032..101684 Replicon plasmid Plas1
Accession NZ_CP052103
Organism Ralstonia solanacearum strain FJAT15252.F50

Toxin (Protein)


Gene name higB Uniprot ID A0A454TTN3
Locus tag HI806_RS19390 Protein ID WP_038962847.1
Coordinates 101032..101376 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag HI806_RS19395 Protein ID WP_020425351.1
Coordinates 101373..101684 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HI806_RS19375 96728..97891 - 1164 WP_016725329.1 2-methylcitrate synthase -
HI806_RS19380 97943..98839 - 897 WP_038962849.1 methylisocitrate lyase -
HI806_RS19385 99032..100981 + 1950 WP_023470006.1 propionate catabolism operon regulatory protein PrpR -
HI806_RS19390 101032..101376 + 345 WP_038962847.1 hypothetical protein Toxin
HI806_RS19395 101373..101684 + 312 WP_020425351.1 transcriptional regulator Antitoxin
HI806_RS19400 101824..102633 - 810 WP_043885575.1 DUF2242 domain-containing protein -
HI806_RS19405 104025..105011 - 987 WP_016721870.1 IS5 family transposase -
HI806_RS19410 105067..106392 + 1326 WP_016725321.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cyaB / flgC / flgG / fliM / fliG / fliI / acrB / adeG / cheY / cheB / cheW / motA 1..2075688 2075688


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-91)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13227.94 Da        Isoelectric Point: 8.4489

>T155490 WP_038962847.1 NZ_CP052103:101032-101376 [Ralstonia solanacearum]
MDATFIELPPFQRLREHYLSDDEYRALQQELLARPDAGDVIKGTGGLRKLRFSDKRRGKGKRGGLRVIDYHWDGGGQFWM
FVVYDKGEADDLSSDERKVLARLLEQEVKARSER

Download         Length: 345 bp

>T155490 NZ_CP068804:3005853-3005960 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11619.65 Da        Isoelectric Point: 10.7132

>AT155490 WP_020425351.1 NZ_CP052103:101373-101684 [Ralstonia solanacearum]
MKRNLFAELKEGMDALAAEREGKMTLRKVKVRVLQPLDVTAEEIKAVRAAAHASQAVMARRLRVNVRTYQNWEQGTAKPN
TQAAVLIKLVEKHPETLQMLEAL

Download         Length: 312 bp

>AT155490 NZ_CP068804:c3005806-3005740 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A454TTN3

Antitoxin

Source ID Structure

References