Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-ohsC/Ldr(toxin)
Location 1917884..1918105 Replicon chromosome
Accession NZ_CP051753
Organism Escherichia coli strain SCU-102

Toxin (Protein)


Gene name ldrD Uniprot ID A0A229AEQ8
Locus tag HHJ21_RS08945 Protein ID WP_000176713.1
Coordinates 1917884..1917991 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name ohsC
Locus tag -
Coordinates 1918039..1918105 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HHJ21_RS08920 1913729..1914811 + 1083 WP_000804726.1 peptide chain release factor 1 -
HHJ21_RS08925 1914811..1915644 + 834 WP_000456478.1 peptide chain release factor N(5)-glutamine methyltransferase -
HHJ21_RS08930 1915641..1916033 + 393 WP_000200378.1 invasion regulator SirB2 -
HHJ21_RS08935 1916037..1916846 + 810 WP_001257044.1 invasion regulator SirB1 -
HHJ21_RS08940 1916882..1917736 + 855 WP_000811065.1 3-deoxy-8-phosphooctulonate synthase -
HHJ21_RS08945 1917884..1917991 - 108 WP_000176713.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- 1918039..1918105 + 67 NuclAT_11 - Antitoxin
- 1918039..1918105 + 67 NuclAT_11 - Antitoxin
- 1918039..1918105 + 67 NuclAT_11 - Antitoxin
- 1918039..1918105 + 67 NuclAT_11 - Antitoxin
- 1918039..1918105 + 67 NuclAT_13 - Antitoxin
- 1918039..1918105 + 67 NuclAT_13 - Antitoxin
- 1918039..1918105 + 67 NuclAT_13 - Antitoxin
- 1918039..1918105 + 67 NuclAT_13 - Antitoxin
- 1918039..1918105 + 67 NuclAT_15 - Antitoxin
- 1918039..1918105 + 67 NuclAT_15 - Antitoxin
- 1918039..1918105 + 67 NuclAT_15 - Antitoxin
- 1918039..1918105 + 67 NuclAT_15 - Antitoxin
- 1918039..1918105 + 67 NuclAT_17 - Antitoxin
- 1918039..1918105 + 67 NuclAT_17 - Antitoxin
- 1918039..1918105 + 67 NuclAT_17 - Antitoxin
- 1918039..1918105 + 67 NuclAT_17 - Antitoxin
- 1918039..1918105 + 67 NuclAT_19 - Antitoxin
- 1918039..1918105 + 67 NuclAT_19 - Antitoxin
- 1918039..1918105 + 67 NuclAT_19 - Antitoxin
- 1918039..1918105 + 67 NuclAT_19 - Antitoxin
- 1918039..1918105 + 67 NuclAT_9 - Antitoxin
- 1918039..1918105 + 67 NuclAT_9 - Antitoxin
- 1918039..1918105 + 67 NuclAT_9 - Antitoxin
- 1918039..1918105 + 67 NuclAT_9 - Antitoxin
- 1918041..1918104 + 64 NuclAT_22 - -
- 1918041..1918104 + 64 NuclAT_22 - -
- 1918041..1918104 + 64 NuclAT_22 - -
- 1918041..1918104 + 64 NuclAT_22 - -
- 1918041..1918104 + 64 NuclAT_24 - -
- 1918041..1918104 + 64 NuclAT_24 - -
- 1918041..1918104 + 64 NuclAT_24 - -
- 1918041..1918104 + 64 NuclAT_24 - -
- 1918041..1918104 + 64 NuclAT_26 - -
- 1918041..1918104 + 64 NuclAT_26 - -
- 1918041..1918104 + 64 NuclAT_26 - -
- 1918041..1918104 + 64 NuclAT_26 - -
- 1918041..1918104 + 64 NuclAT_28 - -
- 1918041..1918104 + 64 NuclAT_28 - -
- 1918041..1918104 + 64 NuclAT_28 - -
- 1918041..1918104 + 64 NuclAT_28 - -
- 1918041..1918104 + 64 NuclAT_30 - -
- 1918041..1918104 + 64 NuclAT_30 - -
- 1918041..1918104 + 64 NuclAT_30 - -
- 1918041..1918104 + 64 NuclAT_30 - -
- 1918041..1918104 + 64 NuclAT_32 - -
- 1918041..1918104 + 64 NuclAT_32 - -
- 1918041..1918104 + 64 NuclAT_32 - -
- 1918041..1918104 + 64 NuclAT_32 - -
- 1918041..1918106 + 66 NuclAT_34 - -
- 1918041..1918106 + 66 NuclAT_34 - -
- 1918041..1918106 + 66 NuclAT_34 - -
- 1918041..1918106 + 66 NuclAT_34 - -
- 1918041..1918106 + 66 NuclAT_36 - -
- 1918041..1918106 + 66 NuclAT_36 - -
- 1918041..1918106 + 66 NuclAT_36 - -
- 1918041..1918106 + 66 NuclAT_36 - -
- 1918041..1918106 + 66 NuclAT_38 - -
- 1918041..1918106 + 66 NuclAT_38 - -
- 1918041..1918106 + 66 NuclAT_38 - -
- 1918041..1918106 + 66 NuclAT_38 - -
- 1918041..1918106 + 66 NuclAT_40 - -
- 1918041..1918106 + 66 NuclAT_40 - -
- 1918041..1918106 + 66 NuclAT_40 - -
- 1918041..1918106 + 66 NuclAT_40 - -
HHJ21_RS08950 1918419..1918526 - 108 WP_000170955.1 small toxic polypeptide LdrA/LdrC -
- 1918579..1918640 + 62 NuclAT_21 - -
- 1918579..1918640 + 62 NuclAT_21 - -
- 1918579..1918640 + 62 NuclAT_21 - -
- 1918579..1918640 + 62 NuclAT_21 - -
- 1918579..1918640 + 62 NuclAT_23 - -
- 1918579..1918640 + 62 NuclAT_23 - -
- 1918579..1918640 + 62 NuclAT_23 - -
- 1918579..1918640 + 62 NuclAT_23 - -
- 1918579..1918640 + 62 NuclAT_25 - -
- 1918579..1918640 + 62 NuclAT_25 - -
- 1918579..1918640 + 62 NuclAT_25 - -
- 1918579..1918640 + 62 NuclAT_25 - -
- 1918579..1918640 + 62 NuclAT_27 - -
- 1918579..1918640 + 62 NuclAT_27 - -
- 1918579..1918640 + 62 NuclAT_27 - -
- 1918579..1918640 + 62 NuclAT_27 - -
- 1918579..1918640 + 62 NuclAT_29 - -
- 1918579..1918640 + 62 NuclAT_29 - -
- 1918579..1918640 + 62 NuclAT_29 - -
- 1918579..1918640 + 62 NuclAT_29 - -
- 1918579..1918640 + 62 NuclAT_31 - -
- 1918579..1918640 + 62 NuclAT_31 - -
- 1918579..1918640 + 62 NuclAT_31 - -
- 1918579..1918640 + 62 NuclAT_31 - -
- 1918579..1918641 + 63 NuclAT_10 - -
- 1918579..1918641 + 63 NuclAT_10 - -
- 1918579..1918641 + 63 NuclAT_10 - -
- 1918579..1918641 + 63 NuclAT_10 - -
- 1918579..1918641 + 63 NuclAT_12 - -
- 1918579..1918641 + 63 NuclAT_12 - -
- 1918579..1918641 + 63 NuclAT_12 - -
- 1918579..1918641 + 63 NuclAT_12 - -
- 1918579..1918641 + 63 NuclAT_14 - -
- 1918579..1918641 + 63 NuclAT_14 - -
- 1918579..1918641 + 63 NuclAT_14 - -
- 1918579..1918641 + 63 NuclAT_14 - -
- 1918579..1918641 + 63 NuclAT_16 - -
- 1918579..1918641 + 63 NuclAT_16 - -
- 1918579..1918641 + 63 NuclAT_16 - -
- 1918579..1918641 + 63 NuclAT_16 - -
- 1918579..1918641 + 63 NuclAT_18 - -
- 1918579..1918641 + 63 NuclAT_18 - -
- 1918579..1918641 + 63 NuclAT_18 - -
- 1918579..1918641 + 63 NuclAT_18 - -
- 1918579..1918641 + 63 NuclAT_20 - -
- 1918579..1918641 + 63 NuclAT_20 - -
- 1918579..1918641 + 63 NuclAT_20 - -
- 1918579..1918641 + 63 NuclAT_20 - -
- 1918579..1918642 + 64 NuclAT_33 - -
- 1918579..1918642 + 64 NuclAT_33 - -
- 1918579..1918642 + 64 NuclAT_33 - -
- 1918579..1918642 + 64 NuclAT_33 - -
- 1918579..1918642 + 64 NuclAT_35 - -
- 1918579..1918642 + 64 NuclAT_35 - -
- 1918579..1918642 + 64 NuclAT_35 - -
- 1918579..1918642 + 64 NuclAT_35 - -
- 1918579..1918642 + 64 NuclAT_37 - -
- 1918579..1918642 + 64 NuclAT_37 - -
- 1918579..1918642 + 64 NuclAT_37 - -
- 1918579..1918642 + 64 NuclAT_37 - -
- 1918579..1918642 + 64 NuclAT_39 - -
- 1918579..1918642 + 64 NuclAT_39 - -
- 1918579..1918642 + 64 NuclAT_39 - -
- 1918579..1918642 + 64 NuclAT_39 - -
HHJ21_RS08955 1918932..1920032 - 1101 WP_001366250.1 sodium-potassium/proton antiporter ChaA -
HHJ21_RS08960 1920302..1920532 + 231 WP_001146444.1 putative cation transport regulator ChaB -
HHJ21_RS08965 1920690..1921385 + 696 WP_001295621.1 glutathione-specific gamma-glutamylcyclotransferase -
HHJ21_RS08970 1921429..1921782 - 354 WP_001169669.1 DsrE/F sulfur relay family protein YchN -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4031.79 Da        Isoelectric Point: 11.4779

>T155283 WP_000176713.1 NZ_CP051753:c1917991-1917884 [Escherichia coli]
MTLTQFAMTFWHDLAAPILAGIITAAIVSWWRNRK

Download         Length: 108 bp

Antitoxin


Download         Length: 67 bp

>AT155283 NZ_CP051753:1918039-1918105 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTATACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A229AEQ8

Antitoxin

Download structure file

References