Detailed information of TA system TA154781

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 4884618..4884840
• Replicon: chromosome
• Accession: NZ_CP051688
• Organism: Escherichia coli strain SCU-387

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: S1NWX0
• Locus tag: HHJ48_RS23730
• Protein ID: WP_001295224.1
• Coordinates: 4884618..4884725 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	4884774..4884840 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HHJ48_RS23705	4879871..4880623	-	753	WP_000279525.1	cellulose biosynthesis protein BcsQ	-
HHJ48_RS23710	4880635..4880823	-	189	WP_001063314.1	YhjR family protein	-
HHJ48_RS23715	4881096..4882667	+	1572	Protein_4637	cellulose biosynthesis protein BcsE	-
HHJ48_RS23720	4882664..4882855	+	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
HHJ48_RS23725	4882852..4884531	+	1680	WP_000191567.1	cellulose biosynthesis protein BcsG	-
HHJ48_RS23730	4884618..4884725	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
-	4884774..4884840	+	67	-	-	Antitoxin
HHJ48_RS23735	4885201..4886472	+	1272	WP_001298005.1	amino acid permease	-
HHJ48_RS23740	4886502..4887506	-	1005	WP_000103577.1	dipeptide ABC transporter ATP-binding subunit DppF	-
HHJ48_RS23745	4887503..4888486	-	984	WP_001540025.1	dipeptide ABC transporter ATP-binding protein	-
HHJ48_RS23750	4888497..4889399	-	903	WP_000084677.1	dipeptide ABC transporter permease DppC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3882.70 Da
• Isoelectric Point: 9.0157

>T154781 WP_001295224.1 NZ_CP051688:c4884725-4884618 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Nucleotide

• Length: 108 bp

>T154781 NZ_CP068279:c3073986-3073883 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin

Nucleotide

• Length: 67 bp

>AT154781 NZ_CP051688:4884774-4884840 [Escherichia coli]
GTCTAGGTTCAAGATTAGCCCCCGTGATATTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A4P7TSJ7

Antitoxin