Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 2031572..2032091 Replicon chromosome
Accession NZ_CP051643
Organism Staphylococcus caprae strain SY333

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag HHJ99_RS09895 Protein ID WP_044466383.1
Coordinates 2031572..2031841 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag HHJ99_RS09900 Protein ID WP_037541721.1
Coordinates 2031834..2032091 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HHJ99_RS09875 2028296..2029054 + 759 WP_044466379.1 tributyrin esterase -
HHJ99_RS09880 2029323..2029634 - 312 WP_044466380.1 SdpI family protein -
HHJ99_RS09885 2029872..2031011 + 1140 WP_044466381.1 CapA family protein -
HHJ99_RS09890 2031062..2031427 - 366 WP_044466382.1 DUF4870 domain-containing protein -
HHJ99_RS09895 2031572..2031841 - 270 WP_044466383.1 Txe/YoeB family addiction module toxin Toxin
HHJ99_RS09900 2031834..2032091 - 258 WP_037541721.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
HHJ99_RS09905 2032281..2033138 + 858 WP_044466384.1 ABC transporter substrate-binding protein -
HHJ99_RS09910 2033253..2034893 - 1641 WP_170080899.1 alpha-keto acid decarboxylase family protein -
HHJ99_RS09915 2035065..2035511 + 447 WP_002444594.1 MarR family winged helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10565.23 Da        Isoelectric Point: 10.1797

>T154593 WP_044466383.1 NZ_CP051643:c2031841-2031572 [Staphylococcus caprae]
MNKLNVTFTTRAFKDYQFWQQHNLGNFKKINTLLKSIARDGCIEGIGKPEALKGNYEGYYSRRITIEHRLVYKIKNDSIF
IVSCRFHYL

Download         Length: 270 bp

>T154593 NZ_CP068153:34941-35093 [Escherichia coli]
ATGCCACAGCGAACGTTTTTAATGATGTTAATCGTCATCTGTGTGACGATTCTGTGTTTTGTCTGGATGGTGAGGGATTC
GCTTTGCGTACTCCGGCTCCAGCAGGGAAACACAGTGCTTGTGGCAACGTTAGCCTACGAAGTTAAACGTTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9694.68 Da        Isoelectric Point: 4.1677

>AT154593 WP_037541721.1 NZ_CP051643:c2032091-2031834 [Staphylococcus caprae]
MPSINYSNARQNFKELISKVNEDSVTYTITTKEDKNAVILAEKDYNAILETMYLQSNPANVSHLNKSIQELNQNDTITVE
IDDNE

Download         Length: 258 bp

>AT154593 NZ_CP068153:c34891-34829 [Escherichia coli]
TCGAAGCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References