Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_31
Location 1512479..1513031 Replicon chromosome
Accession NZ_CP051625
Organism Pseudomonas sp. gcc21

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag HG264_RS07035 Protein ID WP_169407002.1
Coordinates 1512759..1513031 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag HG264_RS07030 Protein ID WP_169407001.1
Coordinates 1512479..1512769 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HG264_RS07015 1507656..1508798 - 1143 WP_169406998.1 polysaccharide pyruvyl transferase family protein -
HG264_RS07020 1508795..1510030 - 1236 WP_169406999.1 oligosaccharide flippase family protein -
HG264_RS07025 1510058..1511887 - 1830 WP_169407000.1 glutamine--fructose-6-phosphate transaminase (isomerizing) -
HG264_RS07030 1512479..1512769 - 291 WP_169407001.1 helix-turn-helix domain-containing protein Antitoxin
HG264_RS07035 1512759..1513031 - 273 WP_169407002.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HG264_RS07040 1513420..1513926 - 507 WP_169407003.1 transcription/translation regulatory transformer protein RfaH -
HG264_RS07045 1514148..1515554 - 1407 WP_169407004.1 MBL fold metallo-hydrolase -
HG264_RS07050 1516297..1516734 + 438 WP_169407005.1 low molecular weight phosphotyrosine protein phosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(24-82)

Antitoxin

Cro/C1-type helix-turn-helix domain

(31-81)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10029.67 Da        Isoelectric Point: 10.5365

>T154509 WP_169407002.1 NZ_CP051625:c1513031-1512759 [Pseudomonas sp. gcc21]
MSSSISTKTSQQHGPSPRGPCLTAHTKAMGNGLFELRAKAKEGIGRGFFCYMEGERIMVLHAFVKKDQKTPKKELELAKA
RLQEVKKHES

Download         Length: 273 bp

>T154509 NZ_CP068135:c3944387-3944037 [Bacillus cereus]
TTGATTGTAAAACGCGGCGACGTGTATTTTGCAGACCTTTCCCCAGTTGTTGGTTCTGAGCAAGGAGGCGTTCGTCCGGT
TCTTGTCATTCAAAATGACATCGGAAATCGTTTTAGTCCAACGGTGATTGTAGCGGCTATTACTGCACAGATTCAAAAAG
CGAAATTACCCACTCATGTGGAAATTGATGCGAAAAAGTATGGTTTTGAGAGAGATTCTGTTATTTTACTTGAGCAGATT
CGAACAATCGATAAGCAACGCTTAACGGACAAAATCACTCATTTGGATGAAGTGATGATGAGTCGTGTAGATGAAGCGTT
ACAAATTAGTTTAGGACTAATAGATTTTTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10767.21 Da        Isoelectric Point: 8.9890

>AT154509 WP_169407001.1 NZ_CP051625:c1512769-1512479 [Pseudomonas sp. gcc21]
MSLNALKHEAFKNEAVRAEYDNLADEFELIDQLTSMRSKAGLTQEQLAKRIGTAKSNISRLERGRGNPSWETLKKYAHAC
GFRVKLEAVEDTGKIA

Download         Length: 291 bp

>AT154509 NZ_CP068135:c3944679-3944392 [Bacillus cereus]
GTGTCCGAATCAAGTGTAACTACTGAAATCGTGGTTCGGTTGCCAAAGCAAATGGTAACGGAATTGGACGGAATTGGAAA
ACAAGAGAATAAGAATCGCCATGAACTAATTTGCCAGGCAACACAATTGTTATTGCGTCAACATAAGACGAAGAAACGCT
ACCAACATGAATCAATGCGACGTGGGTACATTGAAATGGGAAAAATTAATCTTGGTATTGCATCTGAAGCTTTCTTAGCA
GAGTATGAAGCAGCTCATACAGTAGAACGCTTAGTTAGCGGGGGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References