Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 2226538..2227084 Replicon chromosome
Accession NZ_CP051515
Organism Paraburkholderia aromaticivorans strain AR20-38

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag HF916_RS21775 Protein ID WP_168790883.1
Coordinates 2226538..2226780 (-) Length 81 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag HF916_RS21780 Protein ID WP_168790884.1
Coordinates 2226791..2227084 (-) Length 98 a.a.

Genomic Context

HF916_RS21755HF916_RS21760HF916_RS21770HF916_RS21790HF916_RS21795HF916_RS21765HF916_RS21775HF916_RS21780HF916_RS21785
Location: 2221885..2223489 (1605 bp)
Type: Others
Protein ID: WP_168790879.1
Location: 2223518..2224576 (1059 bp)
Type: Others
Protein ID: WP_168790880.1
Location: 2225541..2226461 (921 bp)
Type: Others
Protein ID: WP_168790882.1
Location: 2228824..2229597 (774 bp)
Type: Others
Protein ID: WP_168790886.1
Location: 2229606..2231288 (1683 bp)
Type: Others
Protein ID: WP_168790887.1
Location: 2224561..2225439 (879 bp)
Type: Others
Protein ID: WP_168790881.1
Location: 2226538..2226780 (243 bp)
Type: Toxin
Protein ID: WP_168790883.1
Location: 2226791..2227084 (294 bp)
Type: Antitoxin
Protein ID: WP_168790884.1
Location: 2227348..2228646 (1299 bp)
Type: Others
Protein ID: WP_206001836.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HF916_RS217552221885..2223489+1605WP_168790879.1iron ABC transporter permease-
HF916_RS217602223518..2224576+1059WP_168790880.1ABC transporter ATP-binding protein-
HF916_RS217652224561..2225439-879WP_168790881.1LysR family transcriptional regulator-
HF916_RS217702225541..2226461+921WP_168790882.1DMT family transporter-
HF916_RS217752226538..2226780-243WP_168790883.1Txe/YoeB family addiction module toxinToxin
HF916_RS217802226791..2227084-294WP_168790884.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
HF916_RS217852227348..2228646-1299WP_206001836.1MFS transporter-
HF916_RS217902228824..2229597+774WP_168790886.1GntR family transcriptional regulator-
HF916_RS217952229606..2231288+1683WP_168790887.1malonate decarboxylase subunit alpha-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-80)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 81 a.a.        Molecular weight: 9537.95 Da        Isoelectric Point: 8.4749

>T154367 WP_168790883.1 NZ_CP051515:c2226780-2226538 [Paraburkholderia aromaticivorans]
MFTDDAWDDYLYWQETDRKVLRKINTLLEECRRDPYRGTGKPEALLGSLSGLWSRRITLADRLVYLPRDGKIYVIACRFH

Download         Length: 243 bp

>T154367 NZ_CP068033:c4592187-4591810 [Klebsiella pneumoniae]
ATGCAAACCCAACCGCTATCCTCCACGCAGGAGGCTTCGCCACGCCCGTCACAGGTGGATATCTGGCAGCAGCTTCTGAG
TCACCTGCTGGATCGTCACTACGGTCTGACGCTTAACGACACGCCATTTGGTCACGATGGCGTGATTCAGGAGCATATCG
ACGCGGGTATCTCACTGTGCGATGCCGTGAATGTTATCGTGGAAAAGTACGATCTGGTGCGCACCGATCGTCCCGGTTTC
AGCGCAGAAACACAGTCGCCGCTTATCAGCAGTATCGATATTCTCCGCGCCCGCAAAGCCACCGGGCTGATGACCCGCAA
CGACTACAGAACGGTGACCGACATCACCACCGGTAAATACCGTGAGGTGCAGCCATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10762.16 Da        Isoelectric Point: 8.0098

>AT154367 WP_168790884.1 NZ_CP051515:c2227084-2226791 [Paraburkholderia aromaticivorans]
MNVLTYSEARAGFKQAMDDVCRDHTPMLITRQTGENVVMVSLEDFNAMQETLYLLSSSKNAQRLARSIAQLNAGSATARE
LLTDEQTQKPQRGGRKG

Download         Length: 294 bp

>AT154367 NZ_CP068033:c4592652-4592239 [Klebsiella pneumoniae]
ATGTCGTCCTGCGCAGTGTCACGCTCAATTAACGTTAATTTAAGGAAAGCTAAATTGTCGAATGAAATACCGGCAGTAAA
CCACGATATCGCTGAACCCTGGTGGGGCCTTAAGCCCACCGTCACACCGTGCTTTGGCGCACGACTGGTGCAGGAGGGCA
ACCAGGTGCACTATCTCGCCGACCGCGCCAGCATCACCGGTCAGTTCAGCGAGGCGGATTTACGCCATCTTGACCAGGCC
TTTCCGGTACTACTCAAACAGCTGGAATTGATGCTGGTTTCCGGTGAACTCAATCCTCACCATCAACACGGCGTTACGCT
CTACGCAAAAGGGTTGACCTGCGAAGCCGATTCACTCGGCTCGCATGGCTACATTTATATTGCGATTTATCCAACGCCTG
CAGCAACCGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References