Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 191283..191788 Replicon chromosome
Accession NZ_CP051488
Organism Kosakonia sp. SMBL-WEM22

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag HF650_RS00965 Protein ID WP_054802690.1
Coordinates 191528..191788 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag HF650_RS00960 Protein ID WP_187802570.1
Coordinates 191283..191531 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HF650_RS00940 187781..188227 - 447 WP_187800807.1 N-acetyltransferase -
HF650_RS00945 188208..188786 - 579 WP_187800808.1 DNA-3-methyladenine glycosylase I -
HF650_RS00950 188934..189614 + 681 WP_187800809.1 autotransporter domain-containing protein -
HF650_RS00955 189856..191058 + 1203 WP_187800810.1 MFS transporter -
HF650_RS00960 191283..191531 + 249 WP_187802570.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
HF650_RS00965 191528..191788 + 261 WP_054802690.1 Txe/YoeB family addiction module toxin Toxin
HF650_RS00970 191892..192323 + 432 WP_187800811.1 organic hydroperoxide resistance protein -
HF650_RS00975 192536..194218 + 1683 WP_187800812.1 kdo(2)-lipid A phosphoethanolamine 7''-transferase -
HF650_RS00990 194550..194750 - 201 WP_187800813.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10250.87 Da        Isoelectric Point: 9.7713

>T154291 WP_054802690.1 NZ_CP051488:191528-191788 [Kosakonia sp. SMBL-WEM22]
MTPRITPEAQADIDFWKQNDPKVKQKIDTLVRDALEHPFQGLGKPEALKHHKPLWSRRITKEHRLVYYIKDDSLIIVSCR
YHYVNL

Download         Length: 261 bp

>T154291 NZ_CP067993:259354-259641 [Stenotrophomonas maltophilia]
ATGAAGATCCAGCGTACCCGTCAGTTCGCGACATGGATTGACGCTCTCAAGGACGTAACCGCACGCGCTCGCATCCTGGC
CCGTATCGGTCGGCTCGCTGAAGGCCATCCCGGAGATCACCGCTATCTGGCGGATGGCGTTTCTGAATTGCGTATCGATG
CAGGACCGGGTTACCGCGTGTACTACACCCAGCGCGGCAGGCAGTTGGTGATTCTCCTGGTTGGAGGCGACAAGGGTTCA
CAGCAGCGCGATATCGAGAAGGCCAGGGAGATTGCGCGTGCCCTGTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9190.22 Da        Isoelectric Point: 4.3588

>AT154291 WP_187802570.1 NZ_CP051488:191283-191531 [Kosakonia sp. SMBL-WEM22]
MQHVNYTDARQNLASLMQQANDELAPILVTRKGAKSVVVIDAEEFASMQETLHLFSNPVNAAHIERSIQQAESGDLQEYT
FE

Download         Length: 249 bp

>AT154291 NZ_CP067993:259700-260002 [Stenotrophomonas maltophilia]
ATGGCCATCAAGAGAAAAGTCGAACTCAAATCATTTGATGTGGCCGAGCATCTTCGGACGCCGGAGGAGATGGCGGCTTA
TCTCGACGCCTGCATCGAAGAAAGCGACGGTGATTCTGCATTTATCGCCAAGGCGCTCGGCGATATCGCTCGCGCTCAGG
GCATGAGCAAGGTTGCGCGTGCGGCGGGCTTGTCGCGTGAGAGTCTGTATCGCGCACTGTCGGGCGAGCGCAGTCCGGAT
TTCGCGACCATCCTGAAGGTGACCCGGGCCCTGGGTGTGCGATTGCACGCCAGCGCTGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References