Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 49987..50694 Replicon chromosome
Accession NZ_CP051488
Organism Kosakonia sp. SMBL-WEM22

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag HF650_RS00245 Protein ID WP_076769309.1
Coordinates 50389..50694 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag HF650_RS00240 Protein ID WP_094422700.1
Coordinates 49987..50388 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HF650_RS00220 45764..46711 + 948 WP_187800709.1 ABC transporter permease -
HF650_RS00225 46708..47691 + 984 WP_139966572.1 ABC transporter ATP-binding protein -
HF650_RS00230 47688..48662 + 975 WP_187800710.1 ATP-binding cassette domain-containing protein -
HF650_RS00235 48736..49929 + 1194 WP_187800711.1 glutathione-dependent formaldehyde dehydrogenase -
HF650_RS00240 49987..50388 - 402 WP_094422700.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
HF650_RS00245 50389..50694 - 306 WP_076769309.1 type II toxin-antitoxin system MqsR family toxin Toxin
HF650_RS00250 50852..51505 - 654 WP_187800712.1 oxygen-insensitive NAD(P)H nitroreductase -
HF650_RS00255 51701..52636 + 936 WP_187802558.1 LysR family transcriptional regulator -
HF650_RS00260 52698..53651 + 954 WP_187800713.1 aldo/keto reductase -
HF650_RS00265 53761..54171 + 411 WP_187800714.1 DUF1311 domain-containing protein -
HF650_RS00270 54251..55423 - 1173 WP_187800715.1 multidrug effflux MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-100)

Antitoxin

Antitoxin MqsA

(3-131)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11603.59 Da        Isoelectric Point: 8.9492

>T154290 WP_076769309.1 NZ_CP051488:c50694-50389 [Kosakonia sp. SMBL-WEM22]
MEKGTPHVRLHIVKRMVLEGKVRTTASAVAGAIELGFNPPPFDEMCAVIQALTSEDFFKSMTAYVDHTVWHDVYRPVWKR
QKLYLKLIVSDDVLIVSFKER

Download         Length: 306 bp

>T154290 NZ_CP067993:c104943-103621 [Stenotrophomonas maltophilia]
ATGGGTACGCTGCGGGTCTGGATGAATGGTGTCGAGGTCGCGCTCTGGGATGATGTCCGGAGCGGCTCTTCCCGGCTTTC
GTACGTCGACTCGTGGATCAGCTCCGCCCAGTCCCGGCCGTTGTCACTCTCACTGCCCCTGCTCCCGGAGGGTGAGAGCC
ATCGGGGCGATGTCGTCAACAACTACTTCGACAACCTTCTTCCCGACAACGCCGTCATCCGCAACCGGATCCGCGACAGG
TTCTCCACGCGCAGCAGCGACACATTCGATCTTCTCGAAGCCATTGGCCGGGATTGCGTCGGCGCAGTGCAACTGCTGCC
GCTTTCGCATACACCGGGGAACATCCAGCAGATTACGTGCGAAGCGTTGGACGAATCAGGCGTCGCTGCGATCCTGCGTC
AGGTGACGGCAGGGAATCTACCTGGCGCACCCACCAGTGATGATGCGTTCCGCATATCCATCGCCGGTGCGCAGGAGAAG
ACGGGACTTCTGCTGCATGCTGGCCAGTGGTGCATTCCTACCGGCAGTACCCCATCCACCCATATCTTCAAGCTGCCGCT
TGGCATTGTGGGCAACATGCGGGCGGACATGCACCAATCCGTCGAGAACGAATGGCTTTGCATGCAACTGCTTTCCGCCT
TTGGAATCCCCGTTGCGAATACGCAGATGGGACGCTTCAAGGACGAACGCGCGCTTATTGTGGAGCGATTCGACCGCCGC
CTTTCTGCGGATCGCCGGTGGTGGCTGCGGCTGCCGCAGGAAGACATGTGCCAGGTCTTCGGTCTGCCCGCTGCCAGGAA
GTATGAATCCGATGGCGGCCCAGGCATCGTGACCATCATGGATCTGCTTCGACAATCCGAGCATTTCGAGGATCGGGCGA
CCTTCTTCAAGACGCAGATTCTTTTCTGGATGTTGGCTGCAACCGATGGACATGCCAAGAACTTCAGTGTTTACCTCGAA
GCCGGTGGACGCTTCCGCCTGACACCCGTCTACGACGTATTGTCGGTGCATCCCATCCTGGGTAGGGGGCCAAACCAGCT
CGACCCGCGAAATGCACAGCTCGCCATGTCCGTCCAGGGCAAGAACCGCCACCGGAAGCTGCACCTTGTGCGACGACGCC
ATTGGAACGAAACCGCACGCGCCTGTGGTGTCGCTGATGGTGCGGAGCCGTGGATCGAAGCGCTGATCGCAGCCGTCGAA
CCCGCCATCGAGCAGGTCACGCGTCAGCTCCCAAGTGATTTCCCCGTAAACGTGTCCGAACCCATTTTCAACGGGCTGCG
CGCTGCGGCGGCACGCCTTTCCAGCATGTCGCCGGACGCCTGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14965.20 Da        Isoelectric Point: 8.4709

>AT154290 WP_094422700.1 NZ_CP051488:c50388-49987 [Kosakonia sp. SMBL-WEM22]
MKCPVCGAAGLKYDTRNIEYRYKGKVTTLTAITGDYCDACGEIIFDRLNGELYSKQVAAFVRKVNAEEVDPQFIATIRKR
FNLDQRQAAEMFGGGANAFSRYETGRVAPPRPLVLLFKALDKHPELFEELKHA

Download         Length: 402 bp

>AT154290 NZ_CP067993:c105204-104947 [Stenotrophomonas maltophilia]
ATGGACAGGCCGCTGCACACGGTGAGGACACCTCAACAACTGGCACCGCTGATGCGTGCGTTCAGGCGCCAGGCGGGCCT
GAGCCAGGCGCAGTTGGCGGCACAGCTCGGCATAAGCCGCCAGGCAGTAGGCGCATTGGAGCGCGACCCGGCATCGGCAA
GCTTCGAACGGCTGATGCGGGTCTGGGCAGTGCTGGGTCTGGAAGTCAGATTGCAGCAGCGAAGCCCCCCGGAGACAACG
TCAACGTTGGAGTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References