Detailed information of TA system TA154283

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 1791815..1791999
• Replicon: chromosome
• Accession: NZ_CP051484
• Organism: Staphylococcus aureus strain NGA71

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A2K4AFL5
• Locus tag: HGO96_RS08930
• Protein ID: WP_000482651.1
• Coordinates: 1791892..1791999 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	1791815..1791875 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HGO96_RS08905	1787359..1788474	-	1116	WP_054189927.1	pyridoxal phosphate-dependent aminotransferase family protein	-
HGO96_RS08910	1788452..1789459	-	1008	WP_001046647.1	biotin synthase BioB	-
HGO96_RS08915	1789461..1790819	-	1359	WP_054189926.1	adenosylmethionine--8-amino-7-oxononanoate transaminase	-
HGO96_RS08920	1790797..1791483	-	687	WP_054189925.1	dethiobiotin synthase	-
HGO96_RS08925	1791538..1791705	-	168	Protein_1725	hypothetical protein	-
-	1791815..1791875	+	61	-	-	Antitoxin
HGO96_RS08930	1791892..1791999	-	108	WP_000482651.1	type I toxin-antitoxin system Fst family toxin	Toxin
HGO96_RS08935	1792133..1792519	-	387	WP_054189924.1	flippase GtxA	-
HGO96_RS08940	1792787..1793929	+	1143	WP_054189923.1	glycerate kinase	-
HGO96_RS08945	1793989..1794642	+	654	WP_054189922.1	hypothetical protein	-
HGO96_RS08950	1794824..1796035	+	1212	WP_054189921.1	multidrug effflux MFS transporter	-
HGO96_RS08955	1796159..1796632	-	474	WP_054189920.1	GyrI-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3984.75 Da
• Isoelectric Point: 11.0582

>T154283 WP_000482651.1 NZ_CP051484:c1791999-1791892 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRSNKKGDK

Nucleotide

• Length: 108 bp

>T154283 NZ_CP067966:c2692885-2691563 [Klebsiella quasipneumoniae]
ATGGCGACGCTCACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCCAACGGGGCGCACAGTTTCCG
CTATGATGACGAGTGGTTGCGCAGCCCGCGCGCCAGGCCGCTCTCCCTCTCGCTGCCGCTGCAGTATGGCAATATCACCG
CCGACGCGGTGTATCACTATTTTGATAACCTGTTGCCCGACAGCCCACAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAACAGCCGTTCGATCTGCTGGCCGAGGTCGGCCGGGATAGCGTAGGAGCGGTGACTCTGCTGCCGCCGGG
AGAAGAGGCGCATCTTGCAGCGTTGCGCTGGCAGACGCTGGATGAGGCGCAACTGACCGCGTTGCTGACCGCCTACCAGT
CGGATATTCCGCTCGGGATGGTGACCGGCCAGGACGATTTTCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACCGCGCTG
CTGCGAATGGGCGAGCACTGGTGTATTCCGCAGGGCACCACCCCGACCACCCATATCATTAAACTGCCCATTGGCGAGAT
AAAACAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAACGAATATCTGTGCCTGGCGCTGGCCAGGGCGTTGG
GCCTGGCGGTGCCGGAGGCGGAGATTATCACCACCCCGCGGATCCGTGCGCTGGCGGTGACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGGCGCGTGCTGCTGCGGCTGCCACAAGAGGATCTGTGTCAGGCATTTGGCATCCCGTCGTCGATGAAATA
CGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCCAGTGAAGCCCTGAAAGACCGCTATG
ACTTTATGAAGTTCATGGTGTTCCAGTGGCTGACCGGGGCAACGGATGGGCATGCGAAGAATTTCTCGCTCTTTCTGCTG
CCCGGCGGCAGCTATCGGCTCACGCCGTTCTACGACATTATTTCGGCATTTCCTGTGCTGGGAGGGACGGGACTGCATCT
GCGCGACCTGAAGCTGTCGATGGGGCTCAACGCCACCCGAGGGCGGAAAACGGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACCGCCAAAGCGGTTAACTTTCCCCGGGATCAGATGCTGGCGATCCTTGACGAGTTTGCCGACCGCGTGCCG
CAGGCCATCGAAAGCGCCCGCCGGACGCTGCCCGCGGACTTTTCCGCCCACGTCTGGCGGGCGATCACGGAGAACATGCT
GAAACTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCGATAG

Antitoxin

Nucleotide

• Length: 61 bp

>AT154283 NZ_CP051484:1791815-1791875 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTATTGCCGTAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2K4AFL5

Antitoxin