Detailed information of TA system TA154242

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2408832..2409016
• Replicon: chromosome
• Accession: NZ_CP051482
• Organism: Staphylococcus aureus strain NGA104a

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A2P7CQJ7
• Locus tag: HGO93_RS11780
• Protein ID: WP_000482647.1
• Coordinates: 2408832..2408939 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2408956..2409016 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HGO93_RS11755	2404204..2404677	+	474	WP_000456497.1	GyrI-like domain-containing protein	-
HGO93_RS11760	2404800..2406011	-	1212	WP_001192075.1	multidrug effflux MFS transporter	-
HGO93_RS11765	2406193..2406852	-	660	WP_000831301.1	membrane protein	-
HGO93_RS11770	2406912..2408054	-	1143	WP_001176871.1	glycerate kinase	-
HGO93_RS11775	2408312..2408698	+	387	WP_000779360.1	flippase GtxA	-
HGO93_RS11780	2408832..2408939	+	108	WP_000482647.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	2408956..2409016	-	61	-	-	Antitoxin
HGO93_RS11785	2409623..2411386	+	1764	WP_001064816.1	ABC transporter ATP-binding protein	-
HGO93_RS11790	2411411..2413144	+	1734	WP_000486494.1	ABC transporter ATP-binding protein	-
HGO93_RS11795	2413375..2413542	+	168	WP_001790576.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.76 Da
• Isoelectric Point: 10.4935

>T154242 WP_000482647.1 NZ_CP051482:2408832-2408939 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T154242 NZ_CP067417:2838661-2839314 [Aeromonas media]
ATGGCCTATGACTATAGCCAGAGCCTGAATCCGCAGAAGGCGCTGATATTCCGGATCGTGCATCGGGATAACCTGGAATG
GATCCTGACCCATGGCCTGTGGGCGGGGAATGGTCAGCAGCAAAGCCCGCACTGGGTGCATATCGGGTTGCCGGAGCTGA
TTGCCAAGCGCGCGCGCCATCCGGTGCCGCTGGCTCCTTACGGCGTGTTGAATGACTATGTGCCCTTCTACTTCACGCCG
TTTTCTCCCATGCTCAGCAATATTCACTCCGGGCGCGGTGTTCCCCGGCGTGAAAATGATGAAATCCTGATCCTGGTTTC
CAGCCTGCATCGCATGGCTGAACTGGGGCTACCGTTTGTGTTTACCGATAGCCATGCCTATTACCAGTGGGCCAATTTCT
ATGTCGACCTTGGCGATCTGGGGCGGATTGACTGGCCACTGTTGCAGCGCCGTGATTTCAAGCGTGATGCGGACGATTTG
AGCAAGCTGGAACGCTATCAGGCCGAGGCCTTGATCCATCAACATTGCCCCATCGAGGCGTTGCTGGGCGTGGTGTGTTA
CAACGAAGAAATAAAGAACAGCGTGGAACAATGCATGAATCGGGTGGGGGTCGCGCGCCCCGTCTATGTCCGTGATGGGT
GGTATTTCAGATGA

Antitoxin

Nucleotide

• Length: 61 bp

>AT154242 NZ_CP051482:c2409016-2408956 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2P7CQJ7

Antitoxin