Detailed information of TA system TA154202

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2045062..2045308
• Replicon: chromosome
• Accession: NZ_CP051466
• Organism: Bacillus subtilis subsp. subtilis strain UCMB5021

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: HC658_RS20965
• Protein ID: WP_109789044.1
• Coordinates: 2045062..2045154 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2045135..2045308 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HC658_RS10160	2040221..2040556	+	336	WP_009967409.1	hypothetical protein	-
HC658_RS10165	2040603..2044208	-	3606	WP_004399367.1	membrane protein	-
HC658_RS10170	2044441..2044773	-	333	WP_026009814.1	hypothetical protein	-
HC658_RS20965	2045062..2045154	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	2045135..2045308	-	174	-	-	Antitoxin
HC658_RS10180	2045423..2046265	-	843	WP_003231327.1	hypothetical protein	-
HC658_RS10185	2046465..2046923	-	459	WP_003231326.1	type II toxin-antitoxin system antitoxin YobK	-
HC658_RS10190	2046933..2048735	-	1803	WP_004399481.1	type II toxin-antitoxin system toxin ribonuclease YobL	-
HC658_RS10195	2048837..2049394	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2031457..2054725	23268

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T154202 WP_109789044.1 NZ_CP051466:2045062-2045154 [Bacillus subtilis subsp. subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

>T154202 NZ_CP067399:959488-959823 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin

Nucleotide

• Length: 174 bp

>AT154202 NZ_CP051466:c2045308-2045135 [Bacillus subtilis subsp. subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin