Detailed information of TA system TA154193

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2044812..2045058
• Replicon: chromosome
• Accession: NZ_CP051465
• Organism: Bacillus subtilis subsp. subtilis strain UCMB5121

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: HC659_RS20915
• Protein ID: WP_109789044.1
• Coordinates: 2044812..2044904 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2044885..2045058 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HC659_RS10120	2039971..2040306	+	336	WP_009967409.1	hypothetical protein	-
HC659_RS10125	2040353..2043958	-	3606	WP_004399367.1	membrane protein	-
HC659_RS10130	2044191..2044523	-	333	WP_026009814.1	hypothetical protein	-
HC659_RS20915	2044812..2044904	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	2044885..2045058	-	174	-	-	Antitoxin
HC659_RS10140	2045173..2046015	-	843	WP_003231327.1	hypothetical protein	-
HC659_RS10145	2046215..2046673	-	459	WP_003231326.1	type II toxin-antitoxin system antitoxin YobK	-
HC659_RS10150	2046683..2048485	-	1803	WP_004399481.1	type II toxin-antitoxin system toxin ribonuclease YobL	-
HC659_RS10155	2048587..2049144	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2031207..2054475	23268

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T154193 WP_109789044.1 NZ_CP051465:2044812-2044904 [Bacillus subtilis subsp. subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

>T154193 NZ_CP067397:4630458-4630742 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGACTTATGAACTGGAATTCGACCCGAGGGCCTTAAAAGAGTGGCATAAGCTGGGCGATACGGTGAAGGCTCAGCTTAA
GAAAAAGTTGGCTGATGTGCTATTGAACCCCAGAATCGACTCTGCCCGTTTAAACGGTCTTCCTGACTGCTATAAAATTA
AGCTTAAATCGTCCGGTTATCGTCTGGTGTACCAGGTTCGGGATGACGTTGTGATTGTGTTTGTTGTTGCGGTCGGCAAG
CGAGAACATTCAGCCGTCTATCACGATACAAACAAACGGCTTTAG

Antitoxin

Nucleotide

• Length: 174 bp

>AT154193 NZ_CP051465:c2045058-2044885 [Bacillus subtilis subsp. subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin