Detailed information of TA system TA154176

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yafN-yafO (relBE)/YafO-YafN
• Location: 2664465..2665159
• Replicon: chromosome
• Accession: NZ_CP051460
• Organism: Dickeya solani strain IFB0421

Toxin (Protein)

• Gene name: yafO
• Uniprot ID: -
• Locus tag: HAT92_RS11755
• Protein ID: WP_026594479.1
• Coordinates: 2664465..2664863 (-)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: yafN
• Uniprot ID: A0A2K8VUD1
• Locus tag: HAT92_RS11760
• Protein ID: WP_022633740.1
• Coordinates: 2664866..2665159 (-)
• Length: 98 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HAT92_RS11725	2659645..2660679	-	1035	WP_022633732.1	harpin HrpZ family protein	-
HAT92_RS11730	2660840..2661250	-	411	WP_022633733.1	hypothetical protein	-
HAT92_RS11735	2661247..2661435	-	189	WP_022633734.1	hypothetical protein	-
HAT92_RS11740	2661470..2663539	-	2070	WP_023637836.1	type III secretion system outer membrane ring subunit SctC	-
HAT92_RS11745	2663532..2663966	-	435	WP_022633737.1	hypothetical protein	-
HAT92_RS11750	2663953..2664180	-	228	WP_022633738.1	type III secretion protein HrpF	-
HAT92_RS11755	2664465..2664863	-	399	WP_026594479.1	type II toxin-antitoxin system YafO family toxin	Toxin
HAT92_RS11760	2664866..2665159	-	294	WP_022633740.1	type I toxin-antitoxin system antitoxin YafN	Antitoxin
HAT92_RS11765	2665377..2666426	-	1050	WP_022633741.1	hypothetical protein	-
HAT92_RS11770	2666966..2668126	+	1161	WP_022633742.1	alpha/beta fold hydrolase	-
HAT92_RS11775	2668137..2669450	-	1314	WP_022633743.1	lytic murein transglycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2663953..2673880	9927

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase toxin YafO (27-130)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 15230.56 Da
• Isoelectric Point: 8.4931

>T154176 WP_026594479.1 NZ_CP051460:c2664863-2664465 [Dickeya solani]
IRIFKSTLIRQQLSQQELDDLVADFHAYKQNGVLPDTFGRDAPYDDDRTYPLVKAEQVAHIHLADADAPFPRFLRQFKRT
SDRAHLVYCQGAMDPEACLLIIILKPEAHKMARNNNNMHKIGMMAAAFRMKY

Nucleotide

• Length: 399 bp

>T154176 NZ_CP067394:c2850316-2850050 [Cryobacterium sp. SO1]
GTGACCGCCCGGTGGCACGTTGAGACCACCGAGCAATTTGATCGTCAGTTCCGCAGGTTGGACCGCGCTGTGCAGCGGCG
AGTTCTGACGTACCTCGAAGGCGTCGAACACCTCGACGATCCACGCCAACGCGGGAAAGGCTTGACTGCCAGCCACTCCG
GCGTGTGGCGCTACCGCGTGGGGGACTATCGCATTCTCGCCCAGATTCGGGACGACACGATGGTTGTCCTTGCCCTGACC
GTGGATCACCGCAAGGACGCCTACTGA

Antitoxin

Protein

• Length: 98 a.a.
• Molecular weight: 10934.48 Da
• Isoelectric Point: 5.2082

>AT154176 WP_022633740.1 NZ_CP051460:c2665159-2664866 [Dickeya solani]
MERILAEKSINITELRKNPAKYFIDEPVAVLSNNRPAGYMVSAKVFEELIDLLEAKQETVHTVARFRPTAERLRALADSG
QKLLNDASGKDLTEFTE

Nucleotide

• Length: 294 bp

>AT154176 NZ_CP067394:c2850534-2850313 [Cryobacterium sp. SO1]
GTGACGATCTCGATCCGGCTCACGCTCGATGAAGAAGAGCGCCTGGAGAAGCTGTCGCAGCGCACGGGGCGCTCCAAGAG
CTTCTATGTGCGAGCCGCACTCCGCGCGCATCTGACCGACCTTGAGGATGCCTTCGTGGCGGACGAGGCAGTGGATGCTT
TTGAGGCAGCCGACCGTCGCTCCCGACCGCTCTCGGAGCTGAAGGCCGAGTCTGACTTGTGA

Structures

Antitoxin

• AlphaFold DB: A0A2K8VUD1