Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | yafN-yafO (relBE)/YafO-YafN |
| Location | 2649714..2650408 | Replicon | chromosome |
| Accession | NZ_CP051457 | ||
| Organism | Dickeya solani strain IFB0167 | ||
Toxin (Protein)
| Gene name | yafO | Uniprot ID | - |
| Locus tag | HAT87_RS11675 | Protein ID | WP_026594479.1 |
| Coordinates | 2649714..2650112 (-) | Length | 133 a.a. |
Antitoxin (Protein)
| Gene name | yafN | Uniprot ID | A0A2K8VUD1 |
| Locus tag | HAT87_RS11680 | Protein ID | WP_022633740.1 |
| Coordinates | 2650115..2650408 (-) | Length | 98 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HAT87_RS11645 | 2644894..2645928 | - | 1035 | WP_022633732.1 | harpin HrpZ family protein | - |
| HAT87_RS11650 | 2646089..2646499 | - | 411 | WP_022633733.1 | hypothetical protein | - |
| HAT87_RS11655 | 2646496..2646684 | - | 189 | WP_022633734.1 | hypothetical protein | - |
| HAT87_RS11660 | 2646719..2648788 | - | 2070 | WP_023637836.1 | type III secretion system outer membrane ring subunit SctC | - |
| HAT87_RS11665 | 2648781..2649215 | - | 435 | WP_022633737.1 | hypothetical protein | - |
| HAT87_RS11670 | 2649202..2649429 | - | 228 | WP_022633738.1 | type III secretion protein HrpF | - |
| HAT87_RS11675 | 2649714..2650112 | - | 399 | WP_026594479.1 | type II toxin-antitoxin system YafO family toxin | Toxin |
| HAT87_RS11680 | 2650115..2650408 | - | 294 | WP_022633740.1 | type I toxin-antitoxin system antitoxin YafN | Antitoxin |
| HAT87_RS11685 | 2650626..2651675 | - | 1050 | WP_022633741.1 | hypothetical protein | - |
| HAT87_RS11690 | 2652215..2653375 | + | 1161 | WP_022633742.1 | alpha/beta fold hydrolase | - |
| HAT87_RS11695 | 2653386..2654699 | - | 1314 | WP_022633743.1 | lytic murein transglycosylase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 2649202..2659130 | 9928 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 133 a.a. Molecular weight: 15230.56 Da Isoelectric Point: 8.4931
>T154138 WP_026594479.1 NZ_CP051457:c2650112-2649714 [Dickeya solani]
IRIFKSTLIRQQLSQQELDDLVADFHAYKQNGVLPDTFGRDAPYDDDRTYPLVKAEQVAHIHLADADAPFPRFLRQFKRT
SDRAHLVYCQGAMDPEACLLIIILKPEAHKMARNNNNMHKIGMMAAAFRMKY
IRIFKSTLIRQQLSQQELDDLVADFHAYKQNGVLPDTFGRDAPYDDDRTYPLVKAEQVAHIHLADADAPFPRFLRQFKRT
SDRAHLVYCQGAMDPEACLLIIILKPEAHKMARNNNNMHKIGMMAAAFRMKY
Download Length: 399 bp
>T154138 NZ_CP067370:1925878-1925980 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 98 a.a. Molecular weight: 10934.48 Da Isoelectric Point: 5.2082
>AT154138 WP_022633740.1 NZ_CP051457:c2650408-2650115 [Dickeya solani]
MERILAEKSINITELRKNPAKYFIDEPVAVLSNNRPAGYMVSAKVFEELIDLLEAKQETVHTVARFRPTAERLRALADSG
QKLLNDASGKDLTEFTE
MERILAEKSINITELRKNPAKYFIDEPVAVLSNNRPAGYMVSAKVFEELIDLLEAKQETVHTVARFRPTAERLRALADSG
QKLLNDASGKDLTEFTE
Download Length: 294 bp
>AT154138 NZ_CP067370:c1925987-1925842 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|