Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2198351..2198868 Replicon chromosome
Accession NZ_CP051217
Organism Sphingorhabdus sp. JK6

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag HF685_RS10835 Protein ID WP_168819937.1
Coordinates 2198602..2198868 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag HF685_RS10830 Protein ID WP_168819935.1
Coordinates 2198351..2198605 (+) Length 85 a.a.

Genomic Context


HF685_RS10805HF685_RS10820HF685_RS10825HF685_RS10830HF685_RS10835HF685_RS10840HF685_RS10810HF685_RS10815HF685_RS10845HF685_RS10850
Location: 2193681..2194370 (690 bp)
Type: Others
Protein ID: WP_168819927.1
Location: 2196587..2197707 (1121 bp)
Type: Others
Protein ID: Protein_2140
Location: 2197707..2198297 (591 bp)
Type: Others
Protein ID: WP_168819933.1
Location: 2198351..2198605 (255 bp)
Type: Antitoxin
Protein ID: WP_168819935.1
Location: 2198602..2198868 (267 bp)
Type: Toxin
Protein ID: WP_168819937.1
Location: 2198951..2199688 (738 bp)
Type: Others
Protein ID: WP_168819939.1
Location: 2194451..2195359 (909 bp)
Type: Others
Protein ID: WP_168819929.1
Location: 2195359..2196471 (1113 bp)
Type: Others
Protein ID: WP_168819931.1
Location: 2199692..2201253 (1562 bp)
Type: Others
Protein ID: Protein_2145
Location: 2201317..2202215 (899 bp)
Type: Others
Protein ID: Protein_2146
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HF685_RS108052193681..2194370+690WP_168819927.11-acyl-sn-glycerol-3-phosphate acyltransferase-
HF685_RS108102194451..2195359-909WP_168819929.1prephenate/arogenate dehydrogenase family protein-
HF685_RS108152195359..2196471-1113WP_168819931.1histidinol-phosphate transaminase-
HF685_RS108202196587..2197707+1121Protein_2140homoserine O-acetyltransferase-
HF685_RS108252197707..2198297+591WP_168819933.1methionine biosynthesis protein MetW-
HF685_RS108302198351..2198605+255WP_168819935.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
HF685_RS108352198602..2198868+267WP_168819937.1Txe/YoeB family addiction module toxinToxin
HF685_RS108402198951..2199688+738WP_168819939.1hypothetical protein-
HF685_RS108452199692..2201253-1562Protein_2145peptide chain release factor 3-
HF685_RS108502201317..2202215-899Protein_2146aldose 1-epimerase family protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-88)

Antitoxin

(5-73)


Sequences


Toxin        


Download         Length: 89 a.a.        Molecular weight: 10467.99 Da        Isoelectric Point: 9.8407

>T153823 WP_168819937.1 NZ_CP051217:2198602-2198868 [Sphingorhabdus sp. JK6]
VKLLFSGESWPEYKQLRKSDPKLSDRLDALIEECRCHPFKGTGKPEPLRGQLKGWWSRRINREHRLVYRVRGEGDAQVLE
VAQCRYHY

Download         Length: 267 bp

>T153823 NZ_CP067170:c5779-5366 [Paracoccus aestuarii]
ATGTGGCTGATCGACACGAACGTGATCTCCGCCCTGCGGCGGCCCGAACGCGCGCCCGCGGTGGCGCGCTGGCTGCGTGG
GCAAGACCCCGATGCGCTGTTCCTGTCGGTCGTCACCTTGGGCGAGATCGAACGCGGCATCACCCAGCAGGACAGCCGCA
ACCCCGATTTCGCGCGGGATCTGCGGCTGTGGCTGCAACGGACGGAGCTGCTGTTCGCGGACCGCATCCTGCCCTTCGAT
CCGCCCGCGGCGCGGATCTGGGGCCAGCTGTCGGCGCGGATCGGTCATCCCGGTGCGGATCTGATGATCGCGGCCAGCGC
GCTGTCGCGGGGGATGACGGTGGTGACCGGCAATGTCGACGATTTCACGCCATCCGGGGTGCCGGTCCTGAACCCGTTCG
GGGATGTGACCTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9499.96 Da        Isoelectric Point: 4.5188

>AT153823 WP_168819935.1 NZ_CP051217:2198351-2198605 [Sphingorhabdus sp. JK6]
MLLENFSKARANLKALMDRVVEDKIPLKIQRQNGEAVIMISESEWAGMEETIYLLSSPANAKALMESIRQLDAGEGFEPE
EFKK

Download         Length: 255 bp

>AT153823 NZ_CP067170:c6027-5779 [Paracoccus aestuarii]
ATGTGGAATCTTCAGGACGCCAAGACCCGGTTCAGCACCGTCGTCGCCGATGCGCTGGCCGGGCGGCCCCAGCATGTGAC
CCGCCGCGGCAAGCCCGCCGTCGTGGTCCTGTCCGAGGCCGATTACGCCCAGCTGAAGGCCGCCGCGCAGGCATCGCGCG
AAAGCTTCGTCGATCACCTGCTGGCCTTTCCTGCCCAGGACACGGCCCTGTCCCGCGCCTCGGCCGCACCGCGCGACGTC
GCCTTCTGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References