Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2198351..2198868 Replicon chromosome
Accession NZ_CP051217
Organism Sphingorhabdus sp. JK6

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag HF685_RS10835 Protein ID WP_168819937.1
Coordinates 2198602..2198868 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag HF685_RS10830 Protein ID WP_168819935.1
Coordinates 2198351..2198605 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HF685_RS10805 2193681..2194370 + 690 WP_168819927.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
HF685_RS10810 2194451..2195359 - 909 WP_168819929.1 prephenate/arogenate dehydrogenase family protein -
HF685_RS10815 2195359..2196471 - 1113 WP_168819931.1 histidinol-phosphate transaminase -
HF685_RS10820 2196587..2197707 + 1121 Protein_2140 homoserine O-acetyltransferase -
HF685_RS10825 2197707..2198297 + 591 WP_168819933.1 methionine biosynthesis protein MetW -
HF685_RS10830 2198351..2198605 + 255 WP_168819935.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
HF685_RS10835 2198602..2198868 + 267 WP_168819937.1 Txe/YoeB family addiction module toxin Toxin
HF685_RS10840 2198951..2199688 + 738 WP_168819939.1 hypothetical protein -
HF685_RS10845 2199692..2201253 - 1562 Protein_2145 peptide chain release factor 3 -
HF685_RS10850 2201317..2202215 - 899 Protein_2146 aldose 1-epimerase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(5-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10467.99 Da        Isoelectric Point: 9.8407

>T153823 WP_168819937.1 NZ_CP051217:2198602-2198868 [Sphingorhabdus sp. JK6]
VKLLFSGESWPEYKQLRKSDPKLSDRLDALIEECRCHPFKGTGKPEPLRGQLKGWWSRRINREHRLVYRVRGEGDAQVLE
VAQCRYHY

Download         Length: 267 bp

>T153823 NZ_CP067170:c5779-5366 [Paracoccus aestuarii]
ATGTGGCTGATCGACACGAACGTGATCTCCGCCCTGCGGCGGCCCGAACGCGCGCCCGCGGTGGCGCGCTGGCTGCGTGG
GCAAGACCCCGATGCGCTGTTCCTGTCGGTCGTCACCTTGGGCGAGATCGAACGCGGCATCACCCAGCAGGACAGCCGCA
ACCCCGATTTCGCGCGGGATCTGCGGCTGTGGCTGCAACGGACGGAGCTGCTGTTCGCGGACCGCATCCTGCCCTTCGAT
CCGCCCGCGGCGCGGATCTGGGGCCAGCTGTCGGCGCGGATCGGTCATCCCGGTGCGGATCTGATGATCGCGGCCAGCGC
GCTGTCGCGGGGGATGACGGTGGTGACCGGCAATGTCGACGATTTCACGCCATCCGGGGTGCCGGTCCTGAACCCGTTCG
GGGATGTGACCTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9499.96 Da        Isoelectric Point: 4.5188

>AT153823 WP_168819935.1 NZ_CP051217:2198351-2198605 [Sphingorhabdus sp. JK6]
MLLENFSKARANLKALMDRVVEDKIPLKIQRQNGEAVIMISESEWAGMEETIYLLSSPANAKALMESIRQLDAGEGFEPE
EFKK

Download         Length: 255 bp

>AT153823 NZ_CP067170:c6027-5779 [Paracoccus aestuarii]
ATGTGGAATCTTCAGGACGCCAAGACCCGGTTCAGCACCGTCGTCGCCGATGCGCTGGCCGGGCGGCCCCAGCATGTGAC
CCGCCGCGGCAAGCCCGCCGTCGTGGTCCTGTCCGAGGCCGATTACGCCCAGCTGAAGGCCGCCGCGCAGGCATCGCGCG
AAAGCTTCGTCGATCACCTGCTGGCCTTTCCTGCCCAGGACACGGCCCTGTCCCGCGCCTCGGCCGCACCGCGCGACGTC
GCCTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References