Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 239913..240754 Replicon plasmid pUW773mp
Accession NZ_CP051172
Organism Ralstonia solanacearum strain RUN2279

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag HF908_RS19195 Protein ID WP_193028733.1
Coordinates 240239..240754 (+) Length 172 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag HF908_RS19190 Protein ID WP_193028732.1
Coordinates 239913..240242 (+) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HF908_RS19165 234928..235788 + 861 WP_193028728.1 spermidine synthase -
HF908_RS19170 235943..237124 - 1182 WP_193028729.1 DUF1016 family protein -
HF908_RS19175 237183..237405 - 223 Protein_193 hypothetical protein -
HF908_RS19180 237613..238415 + 803 WP_193028730.1 IS5 family transposase -
HF908_RS19185 238604..239743 - 1140 WP_193028731.1 IS701 family transposase -
HF908_RS19190 239913..240242 + 330 WP_193028732.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
HF908_RS19195 240239..240754 + 516 WP_193028733.1 type II toxin-antitoxin system YhaV family toxin Toxin
HF908_RS19200 240920..241882 - 963 WP_193026670.1 IS5 family transposase -
HF908_RS19205 242404..243300 + 897 WP_043899999.1 LysR family transcriptional regulator -
HF908_RS19210 243538..244416 + 879 WP_193028734.1 EamA family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - acrB / fliI / fliM / flgG / flgC / cyaB / motA / cheW / cheB / cheY / adeG 1..1911272 1911272
- flank IS/Tn - - 240920..241882 962


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(16-152)

Antitoxin

PrlF antitoxin

(8-107)


Sequences

Toxin        


Download         Length: 172 a.a.        Molecular weight: 19642.40 Da        Isoelectric Point: 9.6724

>T153713 WP_193028733.1 NZ_CP051172:240239-240754 [Ralstonia solanacearum]
MTAVQPVPLVIHGWTIFAHPLLLDQLDALTRQVEALREKDPSGYVKKNATKRLAAICKLAFDVIPQDPARPEYRQGHTLG
DENKHWFRAKFFQQYRLFFRFHAPSKMIVLAWINDADTKRAYESDDDAYRVFKRMLASGHPPNDWEPLLTEASRQSERLQ
STAGALGTGHR

Download         Length: 516 bp

>T153713 NZ_CP067057:c1905661-1905572 [Rahnella aceris]
GCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATCGTATTCG
GTCTTTTTTT

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12110.59 Da        Isoelectric Point: 4.4731

>AT153713 WP_193028732.1 NZ_CP051172:239913-240242 [Ralstonia solanacearum]
MPVTLEAESTLTDRYQTTVPETVRRALRLGKRDKIHYTIRQTGEVVLTRADDDEAADPVLGQFLRFLAQDIAAHPERLQG
LDTSLVQRIHTLVGGIEVDLDAALSADDE

Download         Length: 330 bp

>AT153713 NZ_CP067057:1905572-1905661 [Rahnella aceris]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References