Detailed information of TA system TA153677

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 34209..34389
• Replicon: chromosome
• Accession: NZ_CP051165
• Organism: Staphylococcus aureus strain NGA84b

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: HF584_RS00215
• Protein ID: WP_001801861.1
• Coordinates: 34294..34389 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	34209..34266 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HF584_RS00185	31457..31900	+	444	WP_054190594.1	DUF1433 domain-containing protein	-
HF584_RS00190	31900..32343	+	444	WP_054190593.1	DUF1433 domain-containing protein	-
HF584_RS00195	32898..33401	-	504	WP_054190592.1	hypothetical protein	-
HF584_RS00200	33423..33785	-	363	WP_054190591.1	colicin E3/pyocin S6 family cytotoxin	-
HF584_RS00205	33817..34084	+	268	Protein_40	transposase	-
HF584_RS00210	34070..34171	-	102	WP_054190590.1	hypothetical protein	-
-	34209..34266	+	58	-	-	Antitoxin
HF584_RS00215	34294..34389	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
HF584_RS00220	34534..34665	+	132	WP_243835228.1	helix-turn-helix domain-containing protein	-
HF584_RS00225	34841..35287	+	447	WP_054190589.1	DUF1433 domain-containing protein	-
HF584_RS00230	36094..36930	-	837	WP_054190587.1	ATP-binding cassette domain-containing protein	-
HF584_RS00235	37307..37879	-	573	WP_054190586.1	hypothetical protein	-
HF584_RS00240	37980..38321	-	342	WP_054190585.1	DUF3969 family protein	-
HF584_RS00245	38362..38988	-	627	WP_054190584.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T153677 WP_001801861.1 NZ_CP051165:c34389-34294 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T153677 NZ_CP067024:c6004028-6003678 [Pseudomonas syringae pv. maculicola]
ATGAATATGTTTGCACTGCGCTTTACCGATGTTGCCCAGCAAAGCCTCGAAGATCAGGTTGAACACCTGGCGGTCTATCA
GGGATTCTCTCCCGCTGCTCAGCGCATAGACACCCTGATTGATGCCATTCAGGACAAGCTCCTGTCCACCCCGTTGGGCT
ACCCGGTCAGTCCTCAATTGAGTGAGCTGGGCGTACTGCACTATCGTGAGTTGAACGCTGACGGATACCGGATCTTTTAC
GAGGTGAGGGAGACAGATGATATTAATGTCATCGTCATAGTGCTCGTATTAGGTGGTAAACAAAGTGTTGAACAGGCACT
AATCCGCTATTGTCTGCTTCAGCCTATTTAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT153677 NZ_CP051165:34209-34266 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin