Detailed information of TA system TA153676

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-SprF2/-
• Location: 18848..19155
• Replicon: chromosome
• Accession: NZ_CP051165
• Organism: Staphylococcus aureus strain NGA84b

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: HF584_RS00105
• Protein ID: WP_077446684.1
• Coordinates: 18848..19024 (+)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	19014..19155 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HF584_RS00085	14066..17851	+	3786	Protein_16	phage tail spike protein	-
HF584_RS00090	17841..17993	+	153	WP_001153681.1	hypothetical protein	-
HF584_RS00095	18040..18327	+	288	WP_001040261.1	hypothetical protein	-
HF584_RS00100	18385..18696	+	312	WP_054190602.1	DUF2951 family protein	-
HF584_RS00105	18848..19024	+	177	WP_077446684.1	type I toxin-antitoxin system toxin PepG1	Toxin
-	19014..19155	-	142	-	-	Antitoxin
HF584_RS00115	19236..19490	+	255	WP_000611512.1	phage holin	-
HF584_RS00120	19502..20257	+	756	WP_000861038.1	CHAP domain-containing protein	-
HF584_RS00125	20448..20939	+	492	WP_000919350.1	staphylokinase	-
HF584_RS00130	21589..21924	+	336	Protein_25	SH3 domain-containing protein	-
HF584_RS00135	22433..22783	+	351	WP_000702262.1	complement inhibitor SCIN-A	-
HF584_RS00140	22836..23096	-	261	WP_001791826.1	hypothetical protein	-
HF584_RS00145	23407..23586	-	180	WP_000669789.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	sak / scn	1..22783	22782

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (30-58)

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6844.44 Da
• Isoelectric Point: 9.9479

>T153676 WP_077446684.1 NZ_CP051165:18848-19024 [Staphylococcus aureus]
MDRWWLSEYKEVVPMLALLKSLERRCLMITISTMLQFGLFLIALIGLVIKFIELSNKK

Nucleotide

• Length: 177 bp

>T153676 NZ_CP067024:5144975-5145379 [Pseudomonas syringae pv. maculicola]
ATGCTCAAATACATGCTCGACACCAATATCTGCATCTTCACTATCAAGAACAAGCCGGTGTCGGTACGTGAGGCCTTCAA
CCTTCATCACGGGCAGCTGTGTATCAGCGCGATCACGTTGATGGAGCTTGTCTACGGCGCAGAAAAGTCTTCCAGCCCCG
AAAGAAATCTTGCTGTTGTAGAAGGTTTTGCAGCGCGTCTTGAATTGCTTCCCTACGATAGCGCCGCCGCGGCTCACACC
GGCATGATCAGAGCCGAGCTGGCCAGAGCGGGTACACCGATTGGCCCGTACGATCAAATGATTGCAGGACATGCCCGCTC
TCTTGGCCTCGTGGTCATCACCAACAACCAGCGTGAATTCCAGCGCGTCGAGGGGCTGAGGGTAGAAGACTGGGTAAGCC
AATGA

Antitoxin

Nucleotide

• Length: 142 bp

>AT153676 NZ_CP051165:c19155-19014 [Staphylococcus aureus]
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGGCTATTTTAGATTAAA
GATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGATGGTTATTTTTTAT

Structures

Antitoxin