153465

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 4682109..4682809 Replicon chromosome
Accession NZ_CP050951
Organism Pseudomonas putida strain JQ581

Toxin (Protein)


Gene name mqsR Uniprot ID A0A7H5R7B0
Locus tag A3L25_RS21400 Protein ID WP_063423101.1
Coordinates 4682513..4682809 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A7H5R787
Locus tag A3L25_RS21395 Protein ID WP_063423100.1
Coordinates 4682109..4682510 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A3L25_RS21375 4677246..4678067 - 822 WP_063424506.1 transporter substrate-binding domain-containing protein -
A3L25_RS21380 4678143..4679072 - 930 WP_063424508.1 FAD-binding protein -
A3L25_RS21385 4679073..4679822 - 750 WP_016498683.1 electron transfer flavoprotein subunit beta/FixA family protein -
A3L25_RS21390 4680355..4682037 + 1683 WP_081237846.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
A3L25_RS21395 4682109..4682510 - 402 WP_063423100.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
A3L25_RS21400 4682513..4682809 - 297 WP_063423101.1 type II toxin-antitoxin system MqsR family toxin Toxin
A3L25_RS21405 4682904..4684229 - 1326 WP_063423102.1 MFS transporter -
A3L25_RS21410 4684303..4684782 - 480 WP_016498680.1 response regulator -
A3L25_RS21415 4685044..4685505 + 462 WP_063423103.1 azurin -
A3L25_RS21420 4685543..4686043 - 501 WP_063423104.1 sigma-70 family RNA polymerase sigma factor -
A3L25_RS21425 4686275..4687456 + 1182 WP_063423105.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-96)

Antitoxin

Zinc finger, MqsA-type

(3-46)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11020.94 Da        Isoelectric Point: 9.7531

>T153465 WP_063423101.1 NZ_CP050951:c4682809-4682513 [Pseudomonas putida]
MEKRTPHCPLERVKVLAAARRISPTGAALRGAKALGIDYPGMLEVISSLERTDFYKSMTSHMDHRVWQDVYRPLTAIGYV
YLKLSVVDDVLIVSFKGL

Download         Length: 297 bp

>T153465 NZ_CP066915:c4803342-4802857 [Klebsiella pneumoniae]
ATGATCTCGGCACCAGAACCGCTTCATGCCGGGCATATTCTTACCCCGTTTTGCTGCGGTATAGATTCCATGGATCACTG
GCTGAAACAGCGGGCGATGAAAAATCAGGTTACTGGCGCATCCCGCACCTTTGTCTGCTGCGACGACGCGAAGGTGATGG
CTTACTACTCACTGGCTTCCAGCGCTGTGACGACAAATACTGCGCCGGGTCGTTTTCGCCGCAATATGCCTGCCCCGATC
CCGGTTGTGGTACTGGGTCGTCTGGCGGTGGATAAATCACTACATGGGAAAGGTGTCGGGCGGGCCCTGGTACGTGATGC
CGGGCTGCGTGTGATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTTCACGCCCTGTCGGATGAAGCACGGG
ATTTTTACCTGCGGGTGGGGTTTGAGCCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGAGGGATTTGGTTAAT
GCCTGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14562.59 Da        Isoelectric Point: 4.7452

>AT153465 WP_063423100.1 NZ_CP050951:c4682510-4682109 [Pseudomonas putida]
MRCPICGGAELAPDVQGMPYSYKGEATVIPDVSGDYCSACGECVLSHDEAMRISNLMTAFDRQVNATVVDPSFIASMRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Download         Length: 402 bp

>AT153465 NZ_CP066915:c4803632-4803339 [Klebsiella pneumoniae]
ATGCCAGCCGCAAACAGCATGTCCATAAAACGCGAAACGTTAAATCTGCGCATTAAACCTGCCGAACGCGATCTTATTGA
TCGGGCGGCGAAAGCCAGAGGGAAAAACCGCACAGACTTTGTGCTGGAGGCCGCCCGCGCTGCCGCTGAGGAAGCGCTGA
TTGAGCAACGCATCATTATGGCCGATCCGCAGGCTTATCAGGAATTTCTCGCTCGTCTGGATCAGGCTCCTGCACCTAAT
GCCGCACTGCGTAAAACTATGCAGACCCCTGCGCCGTGGGAACAGGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7H5R7B0

Antitoxin

Source ID Structure
AlphaFold DB A0A7H5R787

References