Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4739488..4740077 Replicon chromosome
Accession NZ_CP050849
Organism Xanthomonas oryzae pv. oryzicola strain GX2019

Toxin (Protein)


Gene name graT Uniprot ID A0A0C5V8F2
Locus tag HED68_RS21575 Protein ID WP_024712137.1
Coordinates 4739488..4739769 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag HED68_RS21580 Protein ID WP_011260746.1
Coordinates 4739787..4740077 (+) Length 97 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HED68_RS21570 (HED68_21530) 4737132..4739393 + 2262 WP_024712136.1 exodeoxyribonuclease V subunit alpha -
HED68_RS21575 (HED68_21535) 4739488..4739769 + 282 WP_024712137.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HED68_RS21580 (HED68_21540) 4739787..4740077 + 291 WP_011260746.1 HigA family addiction module antitoxin Antitoxin
HED68_RS21585 (HED68_21545) 4741015..4742409 + 1395 WP_149621925.1 type III secretion system effector XopQ -
HED68_RS21590 4742512..4742699 - 188 Protein_4095 hypothetical protein -
HED68_RS21595 (HED68_21550) 4742860..4743192 - 333 WP_011260743.1 hypothetical protein -
HED68_RS21600 (HED68_21555) 4743447..4743752 + 306 WP_224229802.1 hypothetical protein -
HED68_RS21605 (HED68_21560) 4743902..4744324 + 423 WP_044751863.1 PAAR domain-containing protein -
HED68_RS21610 (HED68_21565) 4744327..4744803 + 477 WP_024712141.1 DUF4123 domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-93)

Antitoxin

(14-68)


Sequences


Toxin        


Download         Length: 94 a.a.        Molecular weight: 11125.91 Da        Isoelectric Point: 10.5318

>T153339 WP_024712137.1 NZ_CP050849:4739488-4739769 [Xanthomonas oryzae pv. oryzicola]
MIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQRRGQYNIRINDQWRICFRWM
EGDVVQVEIVDYH

Download         Length: 282 bp

>T153339 NZ_CP066851:c1486507-1486289 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGTCTGATAAACCATTAACTAAAACTGATTATTTGATGCGTTTACGGCGCTGTCAGACAATTGACACTCTGGAGCGCGT
CATTGAGAAAAATAAATATGAATTGTCCGACAATGAGCTGGCTGTATTTTACTCAGCTGCGGATCACCGTCTTGCAGAAT
TGACGATGAACAAACTCTACGACAAGATCCCCTCTTCAGTATGGAAATTCATTCGTTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10420.07 Da        Isoelectric Point: 7.2040

>AT153339 WP_011260746.1 NZ_CP050849:4739787-4740077 [Xanthomonas oryzae pv. oryzicola]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp

>AT153339 NZ_CP066851:c1486909-1486535 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGGACGAATACTCACCCAAAAGACATGATATAGCACAGCTTAAATTTCTTTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAACCATGGCTGGGTTAATGACCCGACCTCAGCAGTCAACCTGCAGCTCAATGAGCTGATAGAGC
ATATTGCAACTTTCGCGCTTAATTATAAAATTAAGTACAATGAAGACAATAAATTGATTGCGCAGATAGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTATGGTATTAATACGCAGGATTTGCAAAAATGGCGTAAATCGGGCAACCGCCT
GTTCCGTTGTTTCGTCAACGCCACCAGGGCCAATCCTGTTAGTTTGTCTTGTTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0C5V8F2


Antitoxin

Source ID Structure

References