Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 2781984..2783437 Replicon chromosome
Accession NZ_CP050849
Organism Xanthomonas oryzae pv. oryzicola strain GX2019

Toxin (Protein)


Gene name rlegT Uniprot ID A0A5C2EYQ5
Locus tag HED68_RS12615 Protein ID WP_047339759.1
Coordinates 2781984..2782835 (-) Length 284 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A0C5V250
Locus tag HED68_RS12620 Protein ID WP_024710981.1
Coordinates 2782832..2783437 (-) Length 202 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HED68_RS12590 (HED68_12535) 2777024..2777986 - 963 WP_044751530.1 IS110 family transposase -
HED68_RS12595 (HED68_12540) 2778211..2778513 - 303 WP_047339762.1 hypothetical protein -
HED68_RS12600 (HED68_12545) 2779386..2779727 - 342 WP_050585837.1 ParB N-terminal domain-containing protein -
HED68_RS12605 (HED68_12550) 2779724..2781010 - 1287 WP_228757531.1 recombinase family protein -
HED68_RS12610 (HED68_12555) 2781427..2781897 - 471 WP_149621647.1 hypothetical protein -
HED68_RS12615 (HED68_12560) 2781984..2782835 - 852 WP_047339759.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
HED68_RS12620 (HED68_12565) 2782832..2783437 - 606 WP_024710981.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
HED68_RS12625 (HED68_12570) 2783681..2784028 - 348 WP_149621648.1 hypothetical protein -
HED68_RS12630 (HED68_12575) 2783979..2784491 - 513 WP_161600049.1 helix-turn-helix domain-containing protein -
HED68_RS12635 (HED68_12580) 2784792..2784968 + 177 WP_014503024.1 hypothetical protein -
HED68_RS12640 (HED68_12585) 2785280..2786365 + 1086 WP_048485514.1 sensor domain-containing diguanylate cyclase -
HED68_RS12645 (HED68_12590) 2786408..2786917 - 510 WP_014503022.1 chemotaxis protein CheW -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2763982..2791728 27746
flank IS/Tn - - 2777024..2777986 962


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(34-262)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(8-55)


Sequences

Toxin        


Download         Length: 284 a.a.        Molecular weight: 31056.91 Da        Isoelectric Point: 7.0657

>T153338 WP_047339759.1 NZ_CP050849:c2782835-2781984 [Xanthomonas oryzae pv. oryzicola]
MSNVAASVRARLRGVAKAQGVDFNQVLVRFALERILYRLSQSEHADRFLLKGALLFTLWYDMPHRATRDADLLGFGASDL
ESVAQTFRDIASVAVDDGIVFDPASVVAEEIRKDAGYAGARILIGGELAKARCRTQIDVGFGDAVTPAPVHSVYPVLLED
LPAPRLRTYPVYTVIAEKLHAIALLGMTNSRMKDYLDLSVLLERESLDIDLLAQAVKATFERRGMAVPAALPIGMTDEFA
HDTSRQALWQAFLKKNELAPEPLAAIVVRLRAALEPALHRAAR

Download         Length: 852 bp

>T153338 NZ_CP066851:c1258156-1257893 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGAATGCCTCCGGCGCCAGCGTCCGCCACATCAACAGCGAAACCTGCATGACCACCTGTTACTCACAAATCCCCAGCGG
CGACTGCCAGGAAGAAGCGGGATTTGAGACCGGGGCGAGCGTTGTTGTGAAGATCTCCGAGCGGGGTTTGATCCTGATTG
CAGAAACGGATGAAGTGAGGGATCTACGGAAGGAGCTTTATCAGGTGAAAAAGTCGATGAAGCATATTAAGGCGGGGGTA
AATAATGTGGTGAACGGGAATTAA

Antitoxin


Download         Length: 202 a.a.        Molecular weight: 22257.92 Da        Isoelectric Point: 9.9253

>AT153338 WP_024710981.1 NZ_CP050849:c2783437-2782832 [Xanthomonas oryzae pv. oryzicola]
MLSDTHTQRVLDLASQKGLLRASDLDAINAPRVVLTRLTAAGVLERVGRGLYRLPDAQGSEFESLAAIATKVPQAVFCLL
TALQFHELTTQLPRQIWIAMPRGSHAPRIGYPPVKMVQMTGDVYAAGIEEHLRDGVRLRVYGAAKTVVDCFKHRNKIGLD
VALEALKDVRAKRKATADDLWRFATVCRVANVMRPYLEAVE

Download         Length: 606 bp

>AT153338 NZ_CP066851:1257903-1258313 [Salmonella enterica subsp. enterica serovar Heidelberg]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCATCCGTTTCTGCAATCAGGATCAAACCCCGCTCGGAGATCTTCACAACAACGCTCGCCCCGGTCTCAAATCCCGCTT
CTTCCTGGCAGTCGCCGCTGGGGATTTGTGAGTAACAGGTGGTCATGCAGGTTTCGCTGTTGATGTGGCGGACGCTGGCG
CCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTCTCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTGAG
CGAGTATGGGCGCGACATCCTGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCCGG
GGCCGTATTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5C2EYQ5

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V250

References