Detailed information of TA system TA153095

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 1493584..1493768
• Replicon: chromosome
• Accession: NZ_CP050690
• Organism: Staphylococcus aureus strain PMB179-1

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A2P7CQJ7
• Locus tag: HCU70_RS07175
• Protein ID: WP_000482647.1
• Coordinates: 1493584..1493691 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	1493708..1493768 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HCU70_RS07150	1488956..1489429	+	474	WP_000456492.1	GyrI-like domain-containing protein	-
HCU70_RS07155	1489552..1490763	-	1212	WP_001192075.1	multidrug effflux MFS transporter	-
HCU70_RS07160	1490945..1491604	-	660	WP_000831295.1	hypothetical protein	-
HCU70_RS07165	1491664..1492806	-	1143	WP_001176863.1	glycerate kinase	-
HCU70_RS07170	1493064..1493450	+	387	WP_000779360.1	flippase GtxA	-
HCU70_RS07175	1493584..1493691	+	108	WP_000482647.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	1493708..1493768	-	61	-	-	Antitoxin
HCU70_RS07180	1494395..1496158	+	1764	WP_001064836.1	ABC transporter ATP-binding protein/permease	-
HCU70_RS07185	1496183..1497916	+	1734	WP_000486496.1	ABC transporter ATP-binding protein/permease	-
HCU70_RS07190	1498147..1498314	+	168	WP_001792506.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.76 Da
• Isoelectric Point: 10.4935

>T153095 WP_000482647.1 NZ_CP050690:1493584-1493691 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T153095 NZ_CP066756:2143048-2143151 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin

Nucleotide

• Length: 61 bp

>AT153095 NZ_CP050690:c1493768-1493708 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2P7CQJ7

Antitoxin