Detailed information of TA system TA153021

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2063183..2063429
• Replicon: chromosome
• Accession: NZ_CP050532
• Organism: Bacillus subtilis subsp. subtilis str. SMY

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: HCN55_RS22070
• Protein ID: WP_109789044.1
• Coordinates: 2063183..2063275 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2063256..2063429 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HCN55_RS10265	2058342..2058677	+	336	WP_009967409.1	hypothetical protein	-
HCN55_RS10270	2058724..2062329	-	3606	WP_004399367.1	membrane protein	-
HCN55_RS10275	2062562..2062894	-	333	WP_026009814.1	hypothetical protein	-
HCN55_RS22070	2063183..2063275	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	2063256..2063429	-	174	-	-	Antitoxin
HCN55_RS10285	2063544..2064386	-	843	WP_003231327.1	hypothetical protein	-
HCN55_RS10290	2064586..2065044	-	459	WP_003231326.1	type II toxin-antitoxin system antitoxin YobK	-
HCN55_RS10295	2065054..2066856	-	1803	WP_004399481.1	type II toxin-antitoxin system toxin ribonuclease YobL	-
HCN55_RS10300	2066958..2067515	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2049166..2072846	23680

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T153021 WP_109789044.1 NZ_CP050532:2063183-2063275 [Bacillus subtilis subsp. subtilis str. SMY]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

>T153021 NZ_CP066739:826851-827156 [Histophilus somni]
ATGTCTGGTAAACAATTAAAGGTCAGTTACTCTAAACAATTTGCTAGAGATTTGACTGATTTGGCAAAACGTTACCCAAA
TGTGCTAGTAGGAACGAAATATATTACAGCAATGCACTGCTTGTTAAACCGCTTGCCATTGCCTGAAAGCTATCAAGATC
ACACATTAGTTGGAGAATGGAAAGGTTATCGAGATTGCCATATTCAAGGGGATTTGGTGCTGATTTACCAATACGTTATA
CACGATGAATTTGATGCGTTGAAATTTTCTCGTTTAAATACCTACTCGCAAACAGCTTCAAAATAG

Antitoxin

Nucleotide

• Length: 174 bp

>AT153021 NZ_CP050532:c2063429-2063256 [Bacillus subtilis subsp. subtilis str. SMY]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin