Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) fst-RNAII/-
Location 310871..311065 Replicon chromosome
Accession NZ_CP050491
Organism Enterococcus faecalis strain EGM183

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag EGM183_RS01580 Protein ID WP_015543884.1
Coordinates 310970..311065 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 310871..310935 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EGM183_RS01565 306496..308244 + 1749 WP_025186938.1 PTS transporter subunit EIIC -
EGM183_RS01570 308235..310268 + 2034 WP_002361171.1 transcription antiterminator -
EGM183_RS01575 310279..310713 + 435 WP_002373201.1 PTS sugar transporter subunit IIA -
- 310871..310935 + 65 NuclAT_15 - Antitoxin
EGM183_RS01580 310970..311065 - 96 WP_015543884.1 type I toxin-antitoxin system Fst family toxin Toxin
EGM183_RS01585 311311..313083 + 1773 WP_002387897.1 PTS mannitol transporter subunit IICBA -
EGM183_RS01590 313098..313535 + 438 WP_002355279.1 PTS sugar transporter subunit IIA -
EGM183_RS01595 313550..314704 + 1155 WP_002355280.1 mannitol-1-phosphate 5-dehydrogenase -
EGM183_RS01600 314772..315887 - 1116 WP_192177144.1 FAD-binding oxidoreductase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 32 a.a.        Molecular weight: 3659.47 Da        Isoelectric Point: 4.6275

>T152912 WP_015543884.1 NZ_CP050491:c311065-310970 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Download         Length: 96 bp

>T152912 NZ_CP066571:31629-31886 [Enterococcus faecium]
ATGATTAAGGCTTGGTCTGATGATGCTTGGGATGATTATCTTTATTGGCATGAGCAAGGAAACAAAAGCAATATAAAAAA
GATTAACAAGTTAATAAAAGATATCGATCGTTCCCCCTTTGCTGGATTAGGAAAACCTGAGCCATTAAAGCATGATTTAT
CTGGAAAATGGTCCAGAAGAATTACAGATGAACATAGACTGATATATAGAGTTGAAAATGAAACGATATTTATTTATTCT
GCAAAAGATCACTATTAA

Antitoxin


Download         Length: 65 bp

>AT152912 NZ_CP050491:310871-310935 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References