Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 4368336..4369032 Replicon chromosome
Accession NZ_CP050150
Organism Hafnia alvei strain A23BA

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag HBA19_RS20005 Protein ID WP_130993059.1
Coordinates 4368721..4369032 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag HBA19_RS20000 Protein ID WP_130971711.1
Coordinates 4368336..4368734 (-) Length 133 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HBA19_RS19990 4364032..4366479 + 2448 WP_096388621.1 glycogen phosphorylase -
HBA19_RS19995 4366609..4368093 - 1485 WP_166493725.1 glycerol-3-phosphate dehydrogenase -
HBA19_RS20000 4368336..4368734 - 399 WP_130971711.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
HBA19_RS20005 4368721..4369032 - 312 WP_130993059.1 type II toxin-antitoxin system MqsR family toxin Toxin
HBA19_RS20010 4369288..4370046 - 759 WP_025799366.1 DeoR/GlpR family transcriptional regulator -
HBA19_RS20015 4370093..4370929 - 837 WP_043489475.1 rhomboid family intramembrane serine protease GlpG -
HBA19_RS20020 4370977..4371306 - 330 WP_025799370.1 thiosulfate sulfurtransferase GlpE -
HBA19_RS20025 4371580..4372011 + 432 WP_043489478.1 hypothetical protein -
HBA19_RS20030 4372146..4372904 - 759 WP_025799373.1 glycerophosphodiester phosphodiesterase -
HBA19_RS20035 4372938..4374014 - 1077 WP_166493726.1 sn-glycerol-3-phosphate import ATP-binding protein UgpC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA/HigA-2

(1-131)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 12047.99 Da        Isoelectric Point: 7.1032

>T152327 WP_130993059.1 NZ_CP050150:c4369032-4368721 [Hafnia alvei]
MEKRTPHCSLEKVRSLIGKGMVRITKSAHRDAELIHFGLADMYRVVCELSPQDFYKSMTTYDDHRIWQDVYHCHLDKVSL
YLKLTVVDDVLIVSFKELDHALP

Download         Length: 312 bp

>T152327 NZ_CP066122:c71300-70998 [Acinetobacter bereziniae]
ATGTACTCAATATATACCACTGAAGTCTTTGATGACTGGTTCACCAAGTTAAAAGACCAGCAGGCAAAAAGACGCATACA
AGTCCGAATTGATCGGGTTGAAGATGGAAACTTTGGAGATACTGAGCCGGTCGGTGAAGGTGTTTCTGAATTACGTTTCT
TCTTTGGGCCAGGCTATAGGATTTATTACTGCAAGCAAGGGCAAAGGGTTGTTATTCTTTTAGCAGGCGGAGATAAGTCT
ACGCAAAGTAAAGATATAAAACTTGCCCTGCAATTGGCACAAGATTTAGAGGAGGAGCTATAA

Antitoxin


Download         Length: 133 a.a.        Molecular weight: 14773.95 Da        Isoelectric Point: 5.7775

>AT152327 WP_130971711.1 NZ_CP050150:c4368734-4368336 [Hafnia alvei]
MHCPECGSKNTIKDYRDIPFTYKGQSTVVKAVGADWCLDCGEGVIFKEESLRIDSILTEFNKQVNASIIDPEYVVAMRKK
LNLSQSEAGEIFGGGVNAFSRYETGKALPHVSTIKLLKLLDKYPELLEEIRN

Download         Length: 399 bp

>AT152327 NZ_CP066122:c70997-70716 [Acinetobacter bereziniae]
ATGGCTATTAAACTTCGCAAATGGGACAGTGCTGAGCATCTTAAAACAGAGGATGATATGCAGGCTTACTTACAAGCATG
TATTGAAGAATCTAATGGCGATGCCGCATTCATTGCAAAGGCTTTAGGTAACATTGCAAAAGCTAAAGGAATGGCTCAAT
TATCACGAGATACAGGCTTAGGCCGAGAAAGTCTTTATAAAGCACTTTCTGGTGATGTTAACCCTAGTTTTGATACTGTG
ATTAAAGTTGTAAAAGCACTGAATTTACGCTTAGCAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References