Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) hok-sok/-
Location 59988..60252 Replicon plasmid pCD90-1-1
Accession NZ_CP050048
Organism Escherichia coli strain 90-1

Toxin (Protein)


Gene name pndA Uniprot ID A0A8H9BDR8
Locus tag G9P52_RS23285 Protein ID WP_023156060.1
Coordinates 60100..60252 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name pndB
Locus tag -
Coordinates 59988..60048 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G9P52_RS23270 55110..56321 - 1212 WP_113078418.1 DsbC family protein -
G9P52_RS23275 56387..57580 - 1194 WP_188028016.1 hypothetical protein -
G9P52_RS23280 57596..59809 - 2214 WP_113078420.1 type IA DNA topoisomerase -
- 59988..60048 - 61 NuclAT_0 - Antitoxin
- 59988..60048 - 61 NuclAT_0 - Antitoxin
- 59988..60048 - 61 NuclAT_0 - Antitoxin
- 59988..60048 - 61 NuclAT_0 - Antitoxin
G9P52_RS23285 60100..60252 + 153 WP_023156060.1 Hok/Gef family protein Toxin
G9P52_RS23290 60324..60575 - 252 WP_001685192.1 hypothetical protein -
G9P52_RS23295 60779..60985 + 207 WP_174217952.1 hypothetical protein -
G9P52_RS23300 61091..62041 - 951 WP_188028017.1 hypothetical protein -
G9P52_RS23305 62110..64254 - 2145 WP_113078422.1 DotA/TraY family protein -
G9P52_RS23310 64289..64513 - 225 WP_050869039.1 hypothetical protein -
G9P52_RS23315 64516..65079 - 564 WP_019842541.1 conjugal transfer protein TraX -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..105583 105583


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(7-46)


Sequences


Toxin        


Download         Length: 51 a.a.        Molecular weight: 5809.14 Da        Isoelectric Point: 8.7948

>T152147 WP_023156060.1 NZ_CP050048:60100-60252 [Escherichia coli]
MPQRTFLMMLIVICVTILCFVWMVRDSLCGFRLQQGNTVLVATLAYEVKR

Download         Length: 153 bp

>T152147 NZ_CP065999:c1689155-1688874 [Kingella denitrificans]
ATGATTACCGATTTCTATTGCAAAGACACGCAAGCCTTGTGGGAAGGAAAGCGCGTAAAGCGTTTTGCCAATATCGAACG
GGTGGCATTAAGGAAATTGCAGCAAATCCATGCCGCCGCCGATTTAAACTTCCTGCGCATCCCGCCGGCAAACCGTTTGG
AAGCACTCAAAGGCGACCGCGAAGGGCAGTACAGCATCTGCGTTAATGACCAGTGGCGTATCTGCTTTATTTGGGAAAAC
GGACACGCAAGCCGCGTGGAAATTGTCGATTATCACGACTAA

Antitoxin


Download         Length: 61 bp

>AT152147 NZ_CP050048:c60048-59988 [Escherichia coli]
GAGGCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References