Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | hok-sok/- |
Location | 59988..60252 | Replicon | plasmid pCD90-1-1 |
Accession | NZ_CP050048 | ||
Organism | Escherichia coli strain 90-1 |
Toxin (Protein)
Gene name | pndA | Uniprot ID | A0A8H9BDR8 |
Locus tag | G9P52_RS23285 | Protein ID | WP_023156060.1 |
Coordinates | 60100..60252 (+) | Length | 51 a.a. |
Antitoxin (RNA)
Gene name | pndB | ||
Locus tag | - | ||
Coordinates | 59988..60048 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
G9P52_RS23270 | 55110..56321 | - | 1212 | WP_113078418.1 | DsbC family protein | - |
G9P52_RS23275 | 56387..57580 | - | 1194 | WP_188028016.1 | hypothetical protein | - |
G9P52_RS23280 | 57596..59809 | - | 2214 | WP_113078420.1 | type IA DNA topoisomerase | - |
- | 59988..60048 | - | 61 | NuclAT_0 | - | Antitoxin |
- | 59988..60048 | - | 61 | NuclAT_0 | - | Antitoxin |
- | 59988..60048 | - | 61 | NuclAT_0 | - | Antitoxin |
- | 59988..60048 | - | 61 | NuclAT_0 | - | Antitoxin |
G9P52_RS23285 | 60100..60252 | + | 153 | WP_023156060.1 | Hok/Gef family protein | Toxin |
G9P52_RS23290 | 60324..60575 | - | 252 | WP_001685192.1 | hypothetical protein | - |
G9P52_RS23295 | 60779..60985 | + | 207 | WP_174217952.1 | hypothetical protein | - |
G9P52_RS23300 | 61091..62041 | - | 951 | WP_188028017.1 | hypothetical protein | - |
G9P52_RS23305 | 62110..64254 | - | 2145 | WP_113078422.1 | DotA/TraY family protein | - |
G9P52_RS23310 | 64289..64513 | - | 225 | WP_050869039.1 | hypothetical protein | - |
G9P52_RS23315 | 64516..65079 | - | 564 | WP_019842541.1 | conjugal transfer protein TraX | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..105583 | 105583 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 51 a.a. Molecular weight: 5809.14 Da Isoelectric Point: 8.7948
>T152147 WP_023156060.1 NZ_CP050048:60100-60252 [Escherichia coli]
MPQRTFLMMLIVICVTILCFVWMVRDSLCGFRLQQGNTVLVATLAYEVKR
MPQRTFLMMLIVICVTILCFVWMVRDSLCGFRLQQGNTVLVATLAYEVKR
Download Length: 153 bp
>T152147 NZ_CP065999:c1689155-1688874 [Kingella denitrificans]
ATGATTACCGATTTCTATTGCAAAGACACGCAAGCCTTGTGGGAAGGAAAGCGCGTAAAGCGTTTTGCCAATATCGAACG
GGTGGCATTAAGGAAATTGCAGCAAATCCATGCCGCCGCCGATTTAAACTTCCTGCGCATCCCGCCGGCAAACCGTTTGG
AAGCACTCAAAGGCGACCGCGAAGGGCAGTACAGCATCTGCGTTAATGACCAGTGGCGTATCTGCTTTATTTGGGAAAAC
GGACACGCAAGCCGCGTGGAAATTGTCGATTATCACGACTAA
ATGATTACCGATTTCTATTGCAAAGACACGCAAGCCTTGTGGGAAGGAAAGCGCGTAAAGCGTTTTGCCAATATCGAACG
GGTGGCATTAAGGAAATTGCAGCAAATCCATGCCGCCGCCGATTTAAACTTCCTGCGCATCCCGCCGGCAAACCGTTTGG
AAGCACTCAAAGGCGACCGCGAAGGGCAGTACAGCATCTGCGTTAATGACCAGTGGCGTATCTGCTTTATTTGGGAAAAC
GGACACGCAAGCCGCGTGGAAATTGTCGATTATCACGACTAA
Antitoxin
Download Length: 61 bp
>AT152147 NZ_CP050048:c60048-59988 [Escherichia coli]
GAGGCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT
GAGGCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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