Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 462876..463702 Replicon chromosome
Accession NZ_CP049990
Organism Pusillimonas sp. DMV24BSW_D

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag G9Q38_RS02175 Protein ID WP_166127370.1
Coordinates 462876..463376 (-) Length 167 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag G9Q38_RS02180 Protein ID WP_166127372.1
Coordinates 463373..463702 (-) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G9Q38_RS02150 457998..458951 - 954 WP_166127362.1 glycosyltransferase family 2 protein -
G9Q38_RS02155 458956..459774 - 819 WP_166127364.1 phytanoyl-CoA dioxygenase family protein -
G9Q38_RS02160 459849..460556 - 708 WP_166127365.1 WbqC family protein -
G9Q38_RS02165 460733..462112 - 1380 WP_166127367.1 hypothetical protein -
G9Q38_RS02170 462462..462641 - 180 WP_166127369.1 hypothetical protein -
G9Q38_RS02175 462876..463376 - 501 WP_166127370.1 type II toxin-antitoxin system YhaV family toxin Toxin
G9Q38_RS02180 463373..463702 - 330 WP_166127372.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
G9Q38_RS02185 463848..464813 - 966 WP_166127373.1 cupin domain-containing protein -
G9Q38_RS02190 464834..465655 - 822 WP_166127375.1 fumarylacetoacetate hydrolase family protein -
G9Q38_RS02195 465652..467316 - 1665 WP_205962327.1 FAD-dependent monooxygenase -
G9Q38_RS02200 467333..468442 - 1110 WP_166127377.1 alcohol dehydrogenase catalytic domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(16-152)

Antitoxin

PrlF antitoxin

(8-107)


Sequences

Toxin        


Download         Length: 167 a.a.        Molecular weight: 19477.28 Da        Isoelectric Point: 10.1905

>T151981 WP_166127370.1 NZ_CP049990:c463376-462876 [Pusillimonas sp. DMV24BSW_D]
MTDKQAVPLVIHGWTIFAHPLFLAQVEALAQQVETLKQKDPVAFIKKNATKRLAAITRLAFDIIPQDPTRPEYRQGNTLG
DDHKHWFRAKFFQQYRLFFRYHAAGKVLVFVWVNDENTKRAYESGDDAYRVFRKMLESGRPPDNWDQLLAEARDEMRRLQ
RFAGNV

Download         Length: 501 bp

>T151981 NZ_CP065865:c5442376-5442029 [Pseudomonas aeruginosa]
ATGTCCCCGGTCGTCATTCGTTTTACTGATACCGCAGAGCAAAGCATCGAAGACCAAGTCCACCACTTGGCTCCATTCCA
AGGTGAACAGGCTGCACTCCAGTCAGTACTGAGCCTTTTGGATGAGATTGAAGAGAAGATTTCACTTGCACCTAAAGGTT
ACCCAGTCAGCCAGCAGGCGAGTCTTCTGGGGGTGCTGAGCTATCGCGAGCTTAATACCGGCCCCTATCGTGTTTTTTAC
GAATTCCACGAAGAGCAAGGCGAGGTGGCAGTGATCTTGGTTTTGCGACAGAAGCAGAGCGTTGAGCAGCAATTGATCCG
CTACTGCTTGGTGGGGCCAATCGAGTGA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12008.48 Da        Isoelectric Point: 4.6647

>AT151981 WP_166127372.1 NZ_CP049990:c463702-463373 [Pusillimonas sp. DMV24BSW_D]
MSATLEVDSTLTERYQTTVPQTVRRALKLGKGDKIHYTIRSNGEVVLTRHTTSSDSDPVLGAFLTFLAADIANHPERLKA
MDASFVQKLQTLTEGVELDLNCALTDDDE

Download         Length: 330 bp

>AT151981 NZ_CP065865:c5442637-5442386 [Pseudomonas aeruginosa]
ATGCGAGTCGAGACAATTAGTTATTTGAAACGTCATGCGGCTGACCTGGATTTATCCGAGCCAATGGTCGTCACGCAGAA
CGGTGTTCCTGCCTATGTGGTTGAGTCATATGCTGAGCGGAAGCAGCGCGATGAAGCAATTGCGCTGGTGAAGTTGCTTG
CGATTGGCTCCCGTCAGTACGCAGAAGGCAAGCATCGCTCTGTTGATGATTTGAAAGCTCGCCTTTCCAGGAGGTTCGCT
CAGCCAGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References