Detailed information of TA system TA151567

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 50830..51071
• Replicon: plasmid unnamed2
• Accession: NZ_CP049777
• Organism: Enterococcus faecalis strain ES-1

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: G7X26_RS14475
• Protein ID: WP_107164701.1
• Coordinates: 50830..50940 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	50980..51071 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G7X26_RS14435	45841..46050	-	210	WP_010830120.1	hypothetical protein	-
G7X26_RS14440	46111..46335	-	225	WP_002395938.1	hypothetical protein	-
G7X26_RS14445	46329..46643	-	315	WP_010774426.1	hypothetical protein	-
G7X26_RS14450	46633..47253	-	621	WP_029656234.1	recombinase family protein	-
G7X26_RS14455	47432..48112	+	681	WP_001015311.1	IS6-like element IS1216 family transposase	-
G7X26_RS14460	48176..48478	+	303	WP_113795156.1	hypothetical protein	-
G7X26_RS14465	48904..50232	+	1329	WP_033919362.1	Y-family DNA polymerase	-
G7X26_RS14470	50229..50579	+	351	WP_010713025.1	hypothetical protein	-
G7X26_RS14475	50830..50940	+	111	WP_107164701.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	50980..51071	-	92	NuclAT_0	-	Antitoxin
-	50980..51071	-	92	NuclAT_0	-	Antitoxin
-	50980..51071	-	92	NuclAT_0	-	Antitoxin
-	50980..51071	-	92	NuclAT_0	-	Antitoxin
G7X26_RS14480	51181..51477	+	297	WP_113795155.1	type III secretion system protein PrgN	-
G7X26_RS14485	51731..52513	+	783	WP_002369746.1	ParA family protein	-
G7X26_RS14490	52506..52862	+	357	WP_002360663.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Conjugative plasmid	fosB3 / erm(B) / aac(6')-aph(2'')	-	1..53121	53121

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4090.89 Da
• Isoelectric Point: 4.1672

>T151567 WP_107164701.1 NZ_CP049777:50830-50940 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDSRK

Nucleotide

• Length: 111 bp

>T151567 NZ_CP065611:c4916000-4915893 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin

Nucleotide

• Length: 92 bp

>AT151567 NZ_CP049777:c51071-50980 [Enterococcus faecalis]
TAAAAATATGTTATACTATAGGTGCGAAACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGA
TTGCTTTTTTTT

Structures

Antitoxin