Detailed information of TA system TA151544

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 361947..362141
• Replicon: chromosome
• Accession: NZ_CP049775
• Organism: Enterococcus faecalis strain ES-1

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: G7X26_RS01880
• Protein ID: WP_015543884.1
• Coordinates: 362046..362141 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	361947..362011 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G7X26_RS01865	357578..359320	+	1743	WP_070416039.1	PTS transporter subunit EIIC	-
G7X26_RS01870	359311..361344	+	2034	WP_016626080.1	transcription antiterminator	-
G7X26_RS01875	361355..361789	+	435	WP_002355276.1	PTS sugar transporter subunit IIA	-
-	361947..362011	+	65	-	-	Antitoxin
G7X26_RS01880	362046..362141	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
G7X26_RS01885	362387..364159	+	1773	WP_023894889.1	PTS mannitol transporter subunit IICBA	-
G7X26_RS01890	364174..364611	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
G7X26_RS01895	364626..365780	+	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
G7X26_RS01900	365849..366964	-	1116	WP_002361174.1	FAD-binding oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T151544 WP_015543884.1 NZ_CP049775:c362141-362046 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T151544 NZ_CP065607:c4102313-4101927 [Escherichia coli]
ATGGGTGTGTATAAGGCAAGGCGATTCAGCCAAAGCACGAAAAAACTTGGTATTCACGATAAAGTTCTCATGGCTGCCGC
TGAAGAAGTGATGCAAGGCATATGGGAGGCTGATTTAGGTAGCGGTGTCATCAAAAAACGGTTACCCCTCCAACAAGGAA
AGAGTGGTGGAGCCAGAACAATTATCTTTTTTAAATCAGCAAATCATGTGTTTTTTTATGATGGTTGGTCCAAGAGTGGT
CTAAGCAGTAAAGGAAGCAAAGAAATCGAAGATGATGAACTGGCAGCCTACAAAAAAATGGCAAATGCATTTCTGGCCTT
TAGCAATAAGCAAATAGAGGATTTGATCGAAACTGGCTTCTTGATTGAGGTGAAAAATGAGCGATAA

Antitoxin

Nucleotide

• Length: 65 bp

>AT151544 NZ_CP049775:361947-362011 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATCAGTAGTAGGGTGTCTTTTTT

Structures

Antitoxin