Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 424278..424788 Replicon chromosome
Accession NZ_CP049683
Organism Polynucleobacter paneuropaeus strain AP-RePozz10-5-G5

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag C2754_RS02255 Protein ID WP_112203283.1
Coordinates 424525..424788 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag C2754_RS02250 Protein ID WP_112203281.1
Coordinates 424278..424535 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2754_RS02215 (C2754_02215) 419388..419831 - 444 WP_112294852.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
C2754_RS02220 (C2754_02220) 419862..420248 - 387 Protein_431 ribosome silencing factor -
C2754_RS02225 (C2754_02225) 420284..420973 - 690 WP_215283875.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
C2754_RS02230 (C2754_02230) 420974..421885 - 912 WP_244973711.1 oxygen-dependent coproporphyrinogen oxidase -
C2754_RS02235 (C2754_02235) 421922..423199 - 1278 WP_112208914.1 phosphoribosylamine--glycine ligase -
C2754_RS02240 (C2754_02240) 423212..423931 - 720 WP_112203279.1 YebC/PmpR family DNA-binding transcriptional regulator -
C2754_RS02250 (C2754_02250) 424278..424535 + 258 WP_112203281.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
C2754_RS02255 (C2754_02255) 424525..424788 + 264 WP_112203283.1 Txe/YoeB family addiction module toxin Toxin
C2754_RS02260 (C2754_02260) 424793..425734 - 942 WP_215286155.1 CysB family HTH-type transcriptional regulator -
C2754_RS02265 (C2754_02265) 425798..426952 - 1155 WP_215274503.1 LPS export ABC transporter permease LptG -
C2754_RS02270 (C2754_02270) 426949..428064 - 1116 WP_112208916.1 LPS export ABC transporter permease LptF -
C2754_RS02275 (C2754_02275) 428175..429752 + 1578 WP_112313771.1 leucyl aminopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10209.77 Da        Isoelectric Point: 9.4082

>T151414 WP_112203283.1 NZ_CP049683:424525-424788 [Polynucleobacter paneuropaeus]
MRSDLVWTSAAWSDYLYWQGQDKKTLKRINLLIKDAIRNPAEGIGKPEALKENLSGLWSRRIDDVNRLVYVIEKDQLVII
ACRYHYS

Download         Length: 264 bp

>T151414 NZ_CP065464:240999-241916 [Klebsiella pneumoniae]
ATGGATATACAGGCGCCTTATTATCGGCAGGTTGCTCTGCTAATGCAGGTTTTACCCTATGTTGCTGTCGAACGGGAATT
TGCGCTGAAAGGTGGCACTGCCATCAATCTCTTTATCCGCGATTTCCCTCGATTATCGGTGGATATCGACCTCGCCTGGG
TGCCCCTGGAAAGCAGAGCCATCGCTTTACCTCATATACGGGATGCGCTTGCACGTATTGCCGCCAATCTGCAACAACAG
GCAGGTATGAGCGCTGTATTACAAGCTAATCGTTCAGATGAGATGCGTGTCATTGTTACTACCGATAGCGCGCAAATAAA
GATAGAGGTTTCACCGGTCGCCCGGGGAACATTATATCCACCACAGGAGCGAGAAGTGGTGGGGGCGGTAGAGGACGTTT
TTGGCTATGCCAGCCTTCCAGTGGTTTCGTTGCCTGACCTCTACGGTGGAAAATTATGCGCGGCGCTGGATCGCCAGCAT
CCCAGAGATTTTTATGACGTGAAATTACTTCTTGATGCGCAGGAGCTTGACCGTCCCATTTTCAATGGGTTTATCGTGTA
TTTACTGAGCCATAATCGGCCTCTGGCTGAAGTGCTGAATCCTCGCTGGAAAGATATTGCTGAACCTTTTTACCGTGAAT
TCAGCGGGATGACATTTGAGACGATAGCCCTGGAGGAACTGACAGCAGTCCCCAACAGGATGATTGCTGCGTTAAAATCC
TGTTTCACACAACAGGATGTCGATTTTTTACTGTCATTTAAACGAGGCGAACCAGACTGGCGTTTAGCGCCGGAAATGCG
TATTCAGGATTTGCCTGCCGTGCAGTGGAAATTGCGCAATATTCATCAGATGCCAGCGATAAAACGCGCTGAGTCATTAG
ATAAACTGGAAAAGGTGCTGGCCGAGTGGCGCAGTTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9638.03 Da        Isoelectric Point: 8.5493

>AT151414 WP_112203281.1 NZ_CP049683:424278-424535 [Polynucleobacter paneuropaeus]
MRVINFSDARNQFKQVIDQVVADSDVTIISRRDAEDAVVMSLDTYNSMMETVHLLKSPANVKHLEKSLAQYRKGQTKAKA
LVDEK

Download         Length: 258 bp

>AT151414 NZ_CP065464:240235-240993 [Klebsiella pneumoniae]
ATGGCAACAAAATTAAACTGGCTGCTGCAAAACAGCGCTCCCGGAGATGTGATCCTTCAGTCCTGGTTAAGCCAGCATGC
CATCTCTCCCTCTCTGTCCTTTAAATACGCGCAAAGTGGCTGGTTAAAAAAAAGAGGCAACGGCGTATATGCGCGTGCGG
GACGTGAGCCGGAGTGGAACGATGCATTAGCATGTTTGCAAAATCAGCTTGCCGCTCCGGTGTATGTTGCGGGGCTCAGT
AGCTTAGTCTGGCAGGGCCGTTCACACTATCTACAGCTAAAACAAAACCAGTGCTGGCTTAGTGTGGAAAATAAAGCGCT
GCTGCCGAAATGGTTCAGGGAATTCCCGGGTGTGGAGTGGATAGTCATATCGGGGAAAAAACTGCCGGTGCTGGATGATA
GATACCGTGTAACGCTTGATATAAAAGGGAAAAAACTCATCGGCAGTGCGCCAGAACTGGCTGCTTACGAGTTGCTGAGC
GCGGTGCCGGGGACCCTCTCATTTAACCACGCTGCAGAGCTTTTCCAGGGGCTGGTTAATCTTAATCCTCGTAAAGTAGA
GTATCTTCTTTCCGTCAGCCAGTCCGTGCAGGCCAAGCGTTTGTATCTCTTCTTCGCCAGTTTTTACGAGCATGGCTGGC
TCAAACGAATCGATAGCCAAAAAATCGATCTGGGAGCGGGCAAGCGGCAAATCGTGGAAAATGGAAAGTTCAATGCTCAA
TACCAAATCACAGTGCCTGAACGCTTTCAAAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References