Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 418283..418793 Replicon chromosome
Accession NZ_CP049679
Organism Polynucleobacter paneuropaeus strain AP-Creno-20-G10

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag G7Z35_RS02235 Protein ID WP_112203283.1
Coordinates 418530..418793 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag G7Z35_RS02230 Protein ID WP_112203281.1
Coordinates 418283..418540 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G7Z35_RS02195 (G7Z35_02205) 413393..413836 - 444 WP_112294852.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
G7Z35_RS02200 (G7Z35_02210) 413867..414253 - 387 Protein_427 ribosome silencing factor -
G7Z35_RS02205 (G7Z35_02215) 414289..414978 - 690 WP_215279409.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
G7Z35_RS02210 (G7Z35_02220) 414979..415890 - 912 WP_112209412.1 oxygen-dependent coproporphyrinogen oxidase -
G7Z35_RS02215 (G7Z35_02225) 415927..417204 - 1278 WP_112208914.1 phosphoribosylamine--glycine ligase -
G7Z35_RS02220 (G7Z35_02230) 417217..417936 - 720 WP_112237704.1 YebC/PmpR family DNA-binding transcriptional regulator -
G7Z35_RS02230 (G7Z35_02240) 418283..418540 + 258 WP_112203281.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
G7Z35_RS02235 (G7Z35_02245) 418530..418793 + 264 WP_112203283.1 Txe/YoeB family addiction module toxin Toxin
G7Z35_RS02240 (G7Z35_02250) 418798..419739 - 942 WP_112203285.1 CysB family HTH-type transcriptional regulator -
G7Z35_RS02245 (G7Z35_02255) 419803..420957 - 1155 WP_215279410.1 LPS export ABC transporter permease LptG -
G7Z35_RS02250 (G7Z35_02260) 420954..422069 - 1116 WP_215279411.1 LPS export ABC transporter permease LptF -
G7Z35_RS02255 (G7Z35_02265) 422180..423757 + 1578 WP_215278939.1 leucyl aminopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10209.77 Da        Isoelectric Point: 9.4082

>T151398 WP_112203283.1 NZ_CP049679:418530-418793 [Polynucleobacter paneuropaeus]
MRSDLVWTSAAWSDYLYWQGQDKKTLKRINLLIKDAIRNPAEGIGKPEALKENLSGLWSRRIDDVNRLVYVIEKDQLVII
ACRYHYS

Download         Length: 264 bp

>T151398 NZ_CP065459:c148351-147881 [Klebsiella pneumoniae]
GTGATCCTCTACAGGCTGACGAAAACAAAGTATCTTTCTACGGCCTGGACCGGATATGGTGCGAAAGAGGCTGGTGGGCG
CTGGAATAGCGTGGGGGTGTCAATGGTATATGTCTCCGAAACAGCATCACTAACGATGCTGGAGACGCTGGTACACCTGC
ATGCGGCACAGATAATGGACTCTTTCACGCTACTGAGTATCGATGTGCCTGATGAACTGATCCAAAGCGCAAACATGGAT
GAATTACCGGACAACTGGGCTGATGAGGATGCGCCTCAGGAACTGGCTGATTACGGAGATGCCTGGTCATTTACCAGGAG
CTCGGTTGCACTGCGTGTTCCCTCAGCCTTATCGCCGGTAGAGTTCAATTATCTGTTAAATCCTGAGCACCCTGAGTTTT
ACGGGATCGTGCAGAAGGCTCAACAGATAGCGTTCCGGTTTGATAGTCGTCTTAAACCTGACAGGAAGTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9638.03 Da        Isoelectric Point: 8.5493

>AT151398 WP_112203281.1 NZ_CP049679:418283-418540 [Polynucleobacter paneuropaeus]
MRVINFSDARNQFKQVIDQVVADSDVTIISRRDAEDAVVMSLDTYNSMMETVHLLKSPANVKHLEKSLAQYRKGQTKAKA
LVDEK

Download         Length: 258 bp

>AT151398 NZ_CP065459:c148791-148348 [Klebsiella pneumoniae]
ATGAAAACATTTAGTTTGTCCTCAACTCCAGCCAGACCACAGCGCCTCTGGCAGGTTGCCGGGTTAAATAATGCTGATGG
CGTAGCGCTTCTGGGCCAAATAAATGAAGGTCTGGACGGGAAGGTGGCGAACCGGATAACTGACTGGGCCAGAATAACCC
AGAATGACCTGAGAAAAATGTCCGGTATCCCGTCAACCACATTTAGCCGCAGTGTGAAGGCTCGTTTTAACCCGGAACAA
AGTGAACGTCTGGTACGTATTATCCGCGTCATTGATCGGGCGGTAGATTTGTTTGAAGGCGACAGGGAAGCCGCACAGAA
GTGGTTGAACGAACCTAACCGGGCATTGAGCTGGAAAGTGCCAGCAGACCTGATGGCATCCGAAACGGGAGCCTATGAGG
TCATTAAGCTGATTACGCGTCTGGAGCATGGGGTGTACTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References