Detailed information of TA system TA151103

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): symER/SymE(toxin)
• Location: 800255..800667
• Replicon: chromosome
• Accession: NZ_CP049278
• Organism: Shigella boydii strain 600690

Toxin (Protein)

• Gene name: symE
• Uniprot ID: -
• Locus tag: G5S56_RS03820
• Protein ID: WP_000132622.1
• Coordinates: 800255..800596 (-)
• Length: 114 a.a.

Antitoxin (RNA)

Gene name	symR
Locus tag	-
Coordinates	800591..800667 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G5S56_RS03805 (796265)	796265..797677	-	1413	WP_078166383.1	PLP-dependent aminotransferase family protein	-
G5S56_RS03810 (797854)	797854..798018	+	165	WP_000394268.1	DUF1127 domain-containing protein	-
G5S56_RS25015 (798115)	798115..798997	+	883	Protein_737	DUF262 domain-containing protein	-
G5S56_RS25020 (799330)	799330..800208	+	879	WP_284522457.1	DUF1524 domain-containing protein	-
G5S56_RS03820 (800255)	800255..800596	-	342	WP_000132622.1	endoribonuclease SymE	Toxin
- (800591)	800591..800667	+	77	NuclAT_17	-	Antitoxin
- (800591)	800591..800667	+	77	NuclAT_17	-	Antitoxin
- (800591)	800591..800667	+	77	NuclAT_17	-	Antitoxin
- (800591)	800591..800667	+	77	NuclAT_17	-	Antitoxin
- (800591)	800591..800667	+	77	NuclAT_18	-	Antitoxin
- (800591)	800591..800667	+	77	NuclAT_18	-	Antitoxin
- (800591)	800591..800667	+	77	NuclAT_18	-	Antitoxin
- (800591)	800591..800667	+	77	NuclAT_18	-	Antitoxin
G5S56_RS03825 (800817)	800817..802553	-	1737	WP_078166381.1	restriction endonuclease subunit S	-
G5S56_RS03830 (802553)	802553..804022	-	1470	WP_004996206.1	type I restriction-modification system subunit M	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	798115..808441	10326

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (20-71)

Sequences

Toxin

Protein

• Length: 114 a.a.
• Molecular weight: 12340.11 Da
• Isoelectric Point: 7.8227

>T151103 WP_000132622.1 NZ_CP049278:c800596-800255 [Shigella boydii]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQSPAPEESE
LMQSLRQVCKLSARKQRQVQEFIGVIAGKQKVA

Nucleotide

• Length: 342 bp

>T151103 NZ_CP065241:4459814-4460182 [Streptomyces clavuligerus]
ATGCACTACCTCACCCTGCCCGAGCTGCTGAACCTCGCGGAGCGGCTGCGGGCGGCCGAGGTGCGCGACTACGGTCTGCT
GGACTCCGCCCTCGCGCGCCCCCAGGCGAGCGTCTTCGGCCAGGACGCCTACCCGGATGTCTGGCAGAAGGCCGCCGCCC
TGATGGAGTCCCTGGCCCGCAACCACGGACTGGTCGACGGCAACAAGCGGATCGCCTGGTATGCCACCTGGGTCTTTCTC
CATGTGAACGGCCATCCGCTGGACCCGGAATTCGACGTGGACGAGGCGGAACGGTTTGTTCTGGACGTCTGCCAGGGGGC
ACTCGACGTCCCCAAGATCGCGTCGGGGCTGCTGCGCTTCGCCCGCTGA

Antitoxin

Nucleotide

• Length: 77 bp

>AT151103 NZ_CP049278:800591-800667 [Shigella boydii]
AGTCATAACTGCTATTCTCCGATAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Structures

Antitoxin