Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 1314802..1315415 Replicon chromosome
Accession NZ_CP049241
Organism Rhizobium pseudoryzae strain DSM 19479

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag G6N78_RS06495 Protein ID WP_165216742.1
Coordinates 1314802..1315083 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag G6N78_RS06500 Protein ID WP_165216744.1
Coordinates 1315113..1315415 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6N78_RS06465 1311315..1311515 - 201 WP_165216731.1 hypothetical protein -
G6N78_RS06470 1311514..1312161 + 648 WP_165216732.1 heme ABC exporter ATP-binding protein CcmA -
G6N78_RS06475 1312499..1313158 + 660 WP_165216734.1 heme exporter protein CcmB -
G6N78_RS06480 1313202..1313960 + 759 WP_165216736.1 heme ABC transporter permease -
G6N78_RS06485 1313962..1314138 + 177 WP_165216738.1 heme exporter protein CcmD -
G6N78_RS06490 1314135..1314734 + 600 WP_165216740.1 DsbE family thiol:disulfide interchange protein -
G6N78_RS06495 1314802..1315083 + 282 WP_165216742.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6N78_RS06500 1315113..1315415 + 303 WP_165216744.1 HigA family addiction module antidote protein Antitoxin
G6N78_RS06505 1315422..1316009 - 588 WP_165216746.1 DUF2585 domain-containing protein -
G6N78_RS06510 1316006..1316653 - 648 WP_165216748.1 septation protein A -
G6N78_RS06515 1316710..1318305 - 1596 WP_165216750.1 signal recognition particle-docking protein FtsY -
G6N78_RS06520 1318321..1319595 - 1275 WP_165216752.1 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase MtaB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(1-93)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(5-96)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10733.15 Da        Isoelectric Point: 7.1682

>T151079 WP_165216742.1 NZ_CP049241:1314802-1315083 [Rhizobium pseudoryzae]
MIRSFRDKRTEAVDAGTIRKGFPAELVRRAQQLLTLIDAARSLDDLRSPPGNRLEKLSGDREGQHSVRINVQWRICFIWK
DGDAEEVEIVDYH

Download         Length: 282 bp

>T151079 NZ_CP065213:201303-201653 [Priestia megaterium]
TTGGTAGTCAAACGTGGCGACGTTTATTTTGCTGACCTATCTCCTGTTGTTGGCTCAGAACAAGGAGGCGTTCGCCCTGT
ACTTGTCATTCAAAATGATATAGGCAATCGTTTTAGCCCAACTGTTATTGTAGCTGCGATCACTGCTCAAATTCAAAAGG
CAAAGTTACCTACGCATGTTGAAATTGATGCAAAGCGCTATGGATTTGAGCGAGATTCAGTTATTTTACTAGAACAAATT
CGTACTATTGATAAACAGAGGCTAACAGACAAGATTACCCATTTAGATGATGAAATGATGGACAGAGTGGATGAAGCCTT
GCAAATCAGTGTAGGACTTATCGACTTTTAG

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11129.02 Da        Isoelectric Point: 8.4935

>AT151079 WP_165216744.1 NZ_CP049241:1315113-1315415 [Rhizobium pseudoryzae]
MTLSKAPAIHPGEILRDLYLEPLGMSPYALAKTLRVPRTRIERIVAEKIGISADTALRLAKFFRTTPELWLNLQSTYDLK
KQSAELAPELAQIPELGEAA

Download         Length: 303 bp

>AT151079 NZ_CP065213:201017-201298 [Priestia megaterium]
GTGTCTGAAGCGAGCGCAACTACAGAAATCCTAGTAAGATTACCGAAAAATTTAGTATCGGAGCTCGATCTTATGGTTAA
ACAAGAAAATGGCAACCGAAGTGATTTTATTCACCAAGCAACAAAATTGTACCTTCGTGAGCGAAAAAAACGCCATATTC
GCGAATCAATGAGACGTGGATATATGGAGATGGCAAAGATAAACTTAAATATTGCTTCCGAGGCTTTTCTAGCAGAGTAT
GAAGCTGATCATACTGTGGATCGTTTAGTAAGCGGGGGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References