Detailed information of TA system TA151043

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/HigB-HigA
• Location: 3455721..3456310
• Replicon: chromosome
• Accession: NZ_CP049205
• Organism: Xanthomonas oryzae pv. oryzae strain K1

Toxin (Protein)

• Gene name: graT
• Uniprot ID: A0A8E2YMU3
• Locus tag: G6N84_RS16230
• Protein ID: WP_011260747.1
• Coordinates: 3455721..3456002 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: G6N84_RS16235
• Protein ID: WP_133265134.1
• Coordinates: 3456020..3456310 (+)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G6N84_RS16225	3453368..3455626	+	2259	WP_041182333.1	exodeoxyribonuclease V subunit alpha	-
G6N84_RS16230	3455721..3456002	+	282	WP_011260747.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
G6N84_RS16235	3456020..3456310	+	291	WP_133265134.1	HigA family addiction module antidote protein	Antitoxin
G6N84_RS16240	3457248..3458642	+	1395	WP_011260745.1	nucleoside hydrolase	-
G6N84_RS16245	3459092..3459424	-	333	WP_011260743.1	hypothetical protein	-
G6N84_RS16250	3459760..3459984	+	225	WP_044751358.1	hypothetical protein	-
G6N84_RS16255	3460122..3460556	+	435	WP_011260742.1	PAAR domain-containing protein	-
G6N84_RS16260	3460559..3461035	+	477	WP_011260741.1	DUF4123 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-1 (4-93)

Antitoxin

• Cro/C1-type helix-turn-helix domain (14-68)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 11070.83 Da
• Isoelectric Point: 10.2139

>T151043 WP_011260747.1 NZ_CP049205:3455721-3456002 [Xanthomonas oryzae pv. oryzae]
MIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQQRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH

Nucleotide

• Length: 282 bp

>T151043 NZ_CP065178:c3251286-3250711 [Pectobacterium quasiaquaticum]
ATGAATCACTCCCCCTATCCCGTGGTACTTGATGCGTGTGTCATTTATCCATCTTTGCTACGGGATTTGCTCATGCATCT
TGGTTTAACAGGGCTATATCAGCCAAAGTGGACGGCACTAATTCAGGAAGAGTGGCAGCGAAATTTGTTGCTAAATAATG
CAGACGTAACGATGGATAAGCTCAGGAACATTGAGCATTTGATGAATAAGGCATTACCTGATGCCAATGTGACTGGTTTC
GAACAACTTATCCCTGCTCTGGTTTTACCTGATGCGGATGATCGACATGTATTGGCCGCTGCGATACGCGCTAATGCAGA
AGTTATCGTCACGGTAAATCTGAAAGATTTTCCAGCAACGGCACTTTCCGAGTTTGCGGTGGAAGCCATGCACCCAGACG
AGTTTATTGCCGATTTATTTGATCTCAATTCTGCACTGGTACTTAAAGCCGTTCGAACTTCACGCACAGCTTTCAGAAAG
CCTCCATTTGATGTGGACGAGTATCTGGATTGTCTCCTGCGCCAGGGGTTACCTATGACGGTAAAAGAACTGGATGCGTA
TCGAGCACTGATTTAA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 10419.13 Da
• Isoelectric Point: 10.0802

>AT151043 WP_133265134.1 NZ_CP049205:3456020-3456310 [Xanthomonas oryzae pv. oryzae]
MTVLPNIHPGDILLEEFLKPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Nucleotide

• Length: 291 bp

>AT151043 NZ_CP065178:c3251747-3251286 [Pectobacterium quasiaquaticum]
ATGAAAAATACTCCTCTAAATAGTTTGAGCCTTCCGGCTCCAAAAGAAATGGAGGCCGCTATTCGTGGACAAAGGCAGCT
TGCAACCTACTTGTCTACGAAGCTGGAAACACAGGAAATTTCGATTCAGGATGCACATGATATTGCCCATCGGATCGAGT
TGCCTACCTCAGCACTCACGCTTTTGATGAGCATCCTTGGCGAACTGGCGGCGGGTAATGCTGTCCAGATTGTCCCCGTG
CAGGCTGAGTTAACGACACAAGAAGCGGCAAATATTCTGAATGTTTCACGGCCACATATGGTGAAGCTTTTGGAAGAAGG
GCATCTTCCTTTCCATAAAACAGGTCGTCATCGCCGCGTGCTTTTTGCTGATTTGATGCAATACAAAGAACAGCGTGAAA
GTGAAAGTATGCAAGCCATGCAGGAGCTGACAGACCGAAGTCAGGAACTCGGGTTTTACTAA